Cardiac complications observed in elderly patients following 2′‐deoxycoformycin therapy

Jean L. Grem, Susan A. King, Hoo G. Chun, Michael R. Grever

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Deoxycoformycin (dCF) is an investigational nucleoside with significant activity in hairy cell leukemia, cutaneous T‐cell lymphoma, and chronic lymphocytic leukemia. During a 4‐year period, 11 patients have experienced cardiac events as a complication of dCF therapy under NCI sponsorship. The cases are presented and recommendations for the administration of dCF to patients with pre‐existing heart disease are made.

Original languageEnglish (US)
Pages (from-to)245-247
Number of pages3
JournalAmerican Journal of Hematology
Volume38
Issue number3
DOIs
StatePublished - Nov 1991

Fingerprint

Pentostatin
Hairy Cell Leukemia
Preexisting Condition Coverage
B-Cell Chronic Lymphocytic Leukemia
Nucleosides
Heart Diseases
Lymphoma
Therapeutics
Skin

Keywords

  • 2′‐deoxycoformycin
  • cardiac side effects
  • pentostatin

ASJC Scopus subject areas

  • Hematology

Cite this

Cardiac complications observed in elderly patients following 2′‐deoxycoformycin therapy. / Grem, Jean L.; King, Susan A.; Chun, Hoo G.; Grever, Michael R.

In: American Journal of Hematology, Vol. 38, No. 3, 11.1991, p. 245-247.

Research output: Contribution to journalArticle

Grem, Jean L. ; King, Susan A. ; Chun, Hoo G. ; Grever, Michael R. / Cardiac complications observed in elderly patients following 2′‐deoxycoformycin therapy. In: American Journal of Hematology. 1991 ; Vol. 38, No. 3. pp. 245-247.
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