Carcinoid crisis and reversible right ventricular dysfunction after embolization in untreated carcinoid syndrome

Farhan Majeed, Thomas Richard Porter, Stefano Tarantolo, Amy L Duhachek-Stapelman, Feng Xie, Abdou Elhendy

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A 59-year-old white male with carcinoid tumor and hepatic metastases underwent hepatic artery embolization. The patient developed carcinoid crisis and a subsequent transthoracic echocardiogram showed classic findings of carcinoid heart disease along with a dilated hypertrophied right ventricle and severely depressed right ventricular ejection fraction. After treatment with octreotide the patient's clinical condition improved and a repeat transthoracic echocardiogram showed a significant improvement and normalization of right ventricular systolic function. Serotonin levels showed a progressive decline that correlated well with the patient's improved clinical condition. These findings suggest that the acute right ventricular dysfunction was secondary to acute carcinoid crisis and resolution resulted in a significant improvement of both right ventricular systolic function and clinical condition.

Original languageEnglish (US)
Pages (from-to)386-389
Number of pages4
JournalEuropean Journal of Echocardiography
Volume8
Issue number5
DOIs
StatePublished - Oct 1 2007

Fingerprint

Right Ventricular Dysfunction
Carcinoid Tumor
Right Ventricular Function
Carcinoid Heart Disease
Octreotide
Hepatic Artery
Stroke Volume
Heart Ventricles
Serotonin
Neoplasm Metastasis
Liver
Therapeutics

Keywords

  • Carcinoid crisis
  • Right ventricle
  • Serotonin

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Carcinoid crisis and reversible right ventricular dysfunction after embolization in untreated carcinoid syndrome. / Majeed, Farhan; Porter, Thomas Richard; Tarantolo, Stefano; Duhachek-Stapelman, Amy L; Xie, Feng; Elhendy, Abdou.

In: European Journal of Echocardiography, Vol. 8, No. 5, 01.10.2007, p. 386-389.

Research output: Contribution to journalArticle

@article{a443882090554e279bc2a8479c593f44,
title = "Carcinoid crisis and reversible right ventricular dysfunction after embolization in untreated carcinoid syndrome",
abstract = "A 59-year-old white male with carcinoid tumor and hepatic metastases underwent hepatic artery embolization. The patient developed carcinoid crisis and a subsequent transthoracic echocardiogram showed classic findings of carcinoid heart disease along with a dilated hypertrophied right ventricle and severely depressed right ventricular ejection fraction. After treatment with octreotide the patient's clinical condition improved and a repeat transthoracic echocardiogram showed a significant improvement and normalization of right ventricular systolic function. Serotonin levels showed a progressive decline that correlated well with the patient's improved clinical condition. These findings suggest that the acute right ventricular dysfunction was secondary to acute carcinoid crisis and resolution resulted in a significant improvement of both right ventricular systolic function and clinical condition.",
keywords = "Carcinoid crisis, Right ventricle, Serotonin",
author = "Farhan Majeed and Porter, {Thomas Richard} and Stefano Tarantolo and Duhachek-Stapelman, {Amy L} and Feng Xie and Abdou Elhendy",
year = "2007",
month = "10",
day = "1",
doi = "10.1016/j.euje.2006.04.008",
language = "English (US)",
volume = "8",
pages = "386--389",
journal = "European Heart Journal Cardiovascular Imaging",
issn = "2047-2404",
publisher = "Oxford University Press",
number = "5",

}

TY - JOUR

T1 - Carcinoid crisis and reversible right ventricular dysfunction after embolization in untreated carcinoid syndrome

AU - Majeed, Farhan

AU - Porter, Thomas Richard

AU - Tarantolo, Stefano

AU - Duhachek-Stapelman, Amy L

AU - Xie, Feng

AU - Elhendy, Abdou

PY - 2007/10/1

Y1 - 2007/10/1

N2 - A 59-year-old white male with carcinoid tumor and hepatic metastases underwent hepatic artery embolization. The patient developed carcinoid crisis and a subsequent transthoracic echocardiogram showed classic findings of carcinoid heart disease along with a dilated hypertrophied right ventricle and severely depressed right ventricular ejection fraction. After treatment with octreotide the patient's clinical condition improved and a repeat transthoracic echocardiogram showed a significant improvement and normalization of right ventricular systolic function. Serotonin levels showed a progressive decline that correlated well with the patient's improved clinical condition. These findings suggest that the acute right ventricular dysfunction was secondary to acute carcinoid crisis and resolution resulted in a significant improvement of both right ventricular systolic function and clinical condition.

AB - A 59-year-old white male with carcinoid tumor and hepatic metastases underwent hepatic artery embolization. The patient developed carcinoid crisis and a subsequent transthoracic echocardiogram showed classic findings of carcinoid heart disease along with a dilated hypertrophied right ventricle and severely depressed right ventricular ejection fraction. After treatment with octreotide the patient's clinical condition improved and a repeat transthoracic echocardiogram showed a significant improvement and normalization of right ventricular systolic function. Serotonin levels showed a progressive decline that correlated well with the patient's improved clinical condition. These findings suggest that the acute right ventricular dysfunction was secondary to acute carcinoid crisis and resolution resulted in a significant improvement of both right ventricular systolic function and clinical condition.

KW - Carcinoid crisis

KW - Right ventricle

KW - Serotonin

UR - http://www.scopus.com/inward/record.url?scp=34548306571&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34548306571&partnerID=8YFLogxK

U2 - 10.1016/j.euje.2006.04.008

DO - 10.1016/j.euje.2006.04.008

M3 - Article

C2 - 17011239

AN - SCOPUS:34548306571

VL - 8

SP - 386

EP - 389

JO - European Heart Journal Cardiovascular Imaging

JF - European Heart Journal Cardiovascular Imaging

SN - 2047-2404

IS - 5

ER -