Cadaveric renal transplantation under cyclosporine-steroid therapy

J. T. Rosenthal, T. R. Hakala, S. Iwatsuki, B. W. Shaw, T. E. Starzl

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Abstract

Ninety-seven cadaveric renal transplants were performed upon 96 patients during 1981. The one year patient mortality was 2.1 per cent. Seventy of the recipients were undergoing trasplantation for the first time. Of these patients, 38 were treated with cyclosporine and steroids with a one year graft survival rate of 89.5 per cent. The other 32 primary recipients were treated with azathioprine and steroids with a one year graft survival rate of 50 per cent. The difference between the cyclosporine-steroid versus conventional therapy groups was significant. Cyclosporine and steroids were also used to treat 26 patients who underwent retransplantation with 27 cadaveric grafts. The one year graft survival time was 77.8 per cent; most of the graft losses were in presensitized patients. The results with retransplantation were twice as good as in historical control groups.

Original languageEnglish (US)
Pages (from-to)309-315
Number of pages7
JournalSurgery Gynecology and Obstetrics
Volume157
Issue number4
StatePublished - Nov 18 1983

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ASJC Scopus subject areas

  • Surgery
  • Obstetrics and Gynecology

Cite this

Rosenthal, J. T., Hakala, T. R., Iwatsuki, S., Shaw, B. W., & Starzl, T. E. (1983). Cadaveric renal transplantation under cyclosporine-steroid therapy. Surgery Gynecology and Obstetrics, 157(4), 309-315.