Il lavaggio broncoalveolare nella diagnosi di cancro.

Translated title of the contribution: Bronchoalveolar lavage in the diagnosis of cancer

A. Pezza, F. De Blasio, S. I. Rennard

Research output: Contribution to journalReview article

Abstract

Bronchoalveolar lavage (BAL) is a widely used clinical procedure. To determine if BAL could provide useful information in the detection of cancer, 850 lavages from 421 patients having BAL for a variety of indications, 50 lavages in patients with Hodgkin's disease and 20 patients with breast cancer undergoing bon marrow transplant were reviewed. BALs were performed with the technique established by Rennard and coll. in which 5 successive 20 cc aliquots are infused in a wedge position. The return from the first aliquot was processed separately from the subsequent four aliquots. Diff-Quick stained cytocentrifuge preparations and Papanicolaou stained millipore filter preparations were analyzed. Thirty-five patients had biopsy-proven lung cancer. In 24 (68.6%) of these, BAL revealed cells diagnostic of malignancy. There were no false positives. Six out of 50 Hodgkin's disease patients had Reed Sternberg cells detected on BAL, and 7/20 breast cancer patients had malignant cells on BAL prior to chemotherapy. In summary, the routine performance of BAL, an easily performed and well-tolerated procedure, may prove to be useful in the routine assessment of patients for cancer.

Original languageItalian
Pages (from-to)231-240
Number of pages10
JournalArchivio Monaldi per le malattie del torace
Volume45
Issue number3
Publication statusPublished - Jan 1 1990

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ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Pezza, A., De Blasio, F., & Rennard, S. I. (1990). Il lavaggio broncoalveolare nella diagnosi di cancro. Archivio Monaldi per le malattie del torace, 45(3), 231-240.