Bronchoalveolar lavage in the assessment of primary and metastatic lung cancer

Stephen Israel Rennard

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Bronchoalveolar lavage (BAL) can provide diagnostic information in cases of primary and metastatic disease to the lung. Diagnostic material can be obtained in about 50% of primary lung cancers, with more accuracy in bronchoalveolar cell carcinoma and adenocarcinoma than in squamous cell carcinoma. The diagnostic yield for cytologic examination is comparable to that of other widely used endoscopic techniques such as transbronchial biopsy. Technical considerations for the performance of BAL for the diagnosis of cancer remain incompletely defined. These include: 1) methods to assure lavage of the appropriate segment, 2) the type of cytologic preparation and stain used, 3) conditions such as viral infections and anti-neoplastic chemotherapy, which can induce changes in airway epithelial cells very difficult to distinguish from malignancy, 4) the optimum technique for the performance of lavage. Lavage may be limited in staging patients with primary lung cancer, but may be useful in staging metastatic lung cancer. In selected clinical situations, BAL will be an important tool for the physician caring for patients in whom malignancy of the lung is suspected.

Original languageEnglish (US)
Pages (from-to)41-43
Number of pages3
JournalRespiration
Volume59
Issue numberSUPPL. 1
DOIs
StatePublished - Jan 1 1992

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Therapeutic Irrigation
Bronchoalveolar Lavage
Lung Neoplasms
Neoplasms
Virus Diseases
Lung Diseases
Squamous Cell Carcinoma
Adenocarcinoma
Coloring Agents
Epithelial Cells
Carcinoma
Physicians
Biopsy
Drug Therapy
Lung

Keywords

  • Bronchoalvcolar lavage
  • Metastatic lung cancer
  • Primary lung cancer

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Bronchoalveolar lavage in the assessment of primary and metastatic lung cancer. / Rennard, Stephen Israel.

In: Respiration, Vol. 59, No. SUPPL. 1, 01.01.1992, p. 41-43.

Research output: Contribution to journalArticle

Rennard, Stephen Israel. / Bronchoalveolar lavage in the assessment of primary and metastatic lung cancer. In: Respiration. 1992 ; Vol. 59, No. SUPPL. 1. pp. 41-43.
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