Branching of fungal hyphae: Regulation, mechanisms and comparison with other branching systems

Steven D. Harris

Research output: Contribution to journalArticle

94 Citations (Scopus)

Abstract

The ability of rapidly growing hyphae to generate new polarity axes that result in the formation of a branch represents one of the most important yet least understood aspects of fungal cell biology. Branching is central to the development of mycelial colonies and also appears to play a key role in fungal interactions with other organisms. This review presents a description of the two major patterns of hyphal branching, apical and lateral, and highlights the roles of internal and external factors in the induction of branch formation. In addition, potential mechanisms underlying branch site selection are outlined, and the possible roles of multiple signaling pathways (i.e., G protein alpha, Cdc42, NDR kinases) and subcellular structures (i.e., the Spitzenkorper, septins) are discussed. Finally, other forms of branching in the plant and animal kingdoms are briefly summarized and compared to hyphal branching.

Original languageEnglish (US)
Pages (from-to)823-832
Number of pages10
JournalMycologia
Volume100
Issue number6
DOIs
StatePublished - Nov 1 2008

Fingerprint

Septins
Hyphae
site selection
GTP-Binding Proteins
hyphae
Cell Biology
branching
Phosphotransferases
protein
animal
G-proteins
cell biology
phosphotransferases (kinases)
organism
regulation
cell (biology)
comparison
organisms
animals

Keywords

  • Apical branch
  • Hyphal morphogenesis
  • Lateral branch
  • Polarity establishment

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Physiology
  • Molecular Biology
  • Genetics
  • Cell Biology

Cite this

Branching of fungal hyphae : Regulation, mechanisms and comparison with other branching systems. / Harris, Steven D.

In: Mycologia, Vol. 100, No. 6, 01.11.2008, p. 823-832.

Research output: Contribution to journalArticle

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