Brain encoding of saltatory velocity through a pulsed pneumotactile array in the lower face

Rebecca Custead, Hyuntaek Oh, Yingying Wang, Steven M Barlow

Research output: Contribution to journalArticle

Abstract

Processing dynamic tactile inputs is a primary function of the somatosensory system. Spatial velocity encoding mechanisms by the nervous system are important for skilled movement production and may play a role in recovery of sensorimotor function following neurological insult. Little is known about tactile velocity encoding in mechanosensory trigeminal networks required for speech, suck, mastication, and facial gesture. High resolution functional magnetic resonance imaging (fMRI) was used to investigate the neural substrates of velocity encoding in the human orofacial somatosensory system during unilateral saltatory pneumotactile stimulation of perioral and buccal hairy skin in 20 neurotypical adults. A custom multichannel, scalable pneumotactile array consisting of 7 TAC-Cells was used to present 5 stimulus conditions: 5 cm/s, 25 cm/s, 65 cm/s, ALL-ON synchronous activation, and ALL-OFF. The spatiotemporal organization of whole-brain blood oxygen level-dependent (BOLD) response was analyzed with general linear modeling (GLM) and fitted response estimates of percent signal change to compare activations associated with each velocity, and the main effect of velocity alone. Sequential saltatory inputs to the right lower face produced localized BOLD responses in 6 key regions of interest (ROI) including; contralateral precentral and postcentral gyri, and ipsilateral precentral, superior temporal (STG), supramarginal gyri (SMG), and cerebellum. The spatiotemporal organization of the evoked BOLD response was highly dependent on velocity, with the greatest amplitude of BOLD signal change recorded during the 5 cm/s presentation in the contralateral hemisphere. Temporal analysis of BOLD response by velocity indicated rapid adaptation via a scalability of networks processing changing pneumotactile velocity cues.

Original languageEnglish (US)
Pages (from-to)58-73
Number of pages16
JournalBrain Research
Volume1677
DOIs
StatePublished - Dec 15 2017

Fingerprint

Oxygen
Brain
Touch
Gestures
Parietal Lobe
Somatosensory Cortex
Cheek
Mastication
Recovery of Function
Frontal Lobe
Cerebellum
Nervous System
Cues
Magnetic Resonance Imaging
Skin

Keywords

  • BOLD
  • Human
  • Network
  • Trigeminal
  • Velocity

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Cite this

Brain encoding of saltatory velocity through a pulsed pneumotactile array in the lower face. / Custead, Rebecca; Oh, Hyuntaek; Wang, Yingying; Barlow, Steven M.

In: Brain Research, Vol. 1677, 15.12.2017, p. 58-73.

Research output: Contribution to journalArticle

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