Bone marrow transplantation for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia

S. J. Forman, M. R. O'Donnell, A. P. Nademanee, D. S. Snyder, P. J. Bierman, G. M. Schmidt, J. L. Fahey, A. S. Stein, P. M. Parker, K. G. Blume

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Abstract

We report the treatment outcome of allogeneic bone marrow transplantation in ten patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. Six patients are alive and well for 6 to 30 months (median 19 months) after transplantation. Four patients died with transplant related complications. In view of the poor prognosis associated with this disease, marrow ablation followed by allogeneic or syngeneic marrow grafting may be the preferred treatment modality if a suitable marrow donor is available.

Original languageEnglish (US)
Pages (from-to)587-588
Number of pages2
JournalBlood
Volume70
Issue number2
StatePublished - Jan 1 1987

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Transplantation (surgical)
Philadelphia Chromosome
Transplants
Chromosomes
Ablation
Bone Marrow Transplantation
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Bone
Bone Marrow
Homologous Transplantation
Transplantation
Tissue Donors
Therapeutics

ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

Cite this

Forman, S. J., O'Donnell, M. R., Nademanee, A. P., Snyder, D. S., Bierman, P. J., Schmidt, G. M., ... Blume, K. G. (1987). Bone marrow transplantation for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood, 70(2), 587-588.

Bone marrow transplantation for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. / Forman, S. J.; O'Donnell, M. R.; Nademanee, A. P.; Snyder, D. S.; Bierman, P. J.; Schmidt, G. M.; Fahey, J. L.; Stein, A. S.; Parker, P. M.; Blume, K. G.

In: Blood, Vol. 70, No. 2, 01.01.1987, p. 587-588.

Research output: Contribution to journalArticle

Forman, SJ, O'Donnell, MR, Nademanee, AP, Snyder, DS, Bierman, PJ, Schmidt, GM, Fahey, JL, Stein, AS, Parker, PM & Blume, KG 1987, 'Bone marrow transplantation for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia', Blood, vol. 70, no. 2, pp. 587-588.
Forman SJ, O'Donnell MR, Nademanee AP, Snyder DS, Bierman PJ, Schmidt GM et al. Bone marrow transplantation for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood. 1987 Jan 1;70(2):587-588.
Forman, S. J. ; O'Donnell, M. R. ; Nademanee, A. P. ; Snyder, D. S. ; Bierman, P. J. ; Schmidt, G. M. ; Fahey, J. L. ; Stein, A. S. ; Parker, P. M. ; Blume, K. G. / Bone marrow transplantation for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. In: Blood. 1987 ; Vol. 70, No. 2. pp. 587-588.
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