Bone marrow transplantation for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia

S. J. Forman, M. R. O'Donnell, A. P. Nademanee, D. S. Snyder, P. J. Bierman, G. M. Schmidt, J. L. Fahey, A. S. Stein, P. M. Parker, K. G. Blume

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Abstract

We report the treatment outcome of allogeneic bone marrow transplantation in ten patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. Six patients are alive and well for 6 to 30 months (median 19 months) after transplantation. Four patients died with transplant related complications. In view of the poor prognosis associated with this disease, marrow ablation followed by allogeneic or syngeneic marrow grafting may be the preferred treatment modality if a suitable marrow donor is available.

Original languageEnglish (US)
Pages (from-to)587-588
Number of pages2
JournalBlood
Volume70
Issue number2
Publication statusPublished - Jan 1 1987

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ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

Cite this

Forman, S. J., O'Donnell, M. R., Nademanee, A. P., Snyder, D. S., Bierman, P. J., Schmidt, G. M., ... Blume, K. G. (1987). Bone marrow transplantation for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood, 70(2), 587-588.