Bone marrow patterns in aplastic anemia: Observations with 1.5-T MR imaging

P. A. Kaplan, R. J. Asleson, Lynell Warren Klassen, M. J. Duggan

Research output: Contribution to journalArticle

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Abstract

Six patients diagnosed as having aplastic anemia underwent magnetic resonance (MR) imaging. The bone marrow in the lumbar spine, pelvis, and proximal femora was examined in each case. One patient had a normal marrow signal intensity (SI) and pattern and was considered cured of disease. The other patients had varying numbers of focal low-SI areas interspersed with high-SI areas in the marrow of the spine. The pelves and proximal femora of all patients had diffuse high-SI marrow without focal abnormalities. Biopsy of a lumbar vertebral body in one patient demonstrated that the focal low-SI areas may have been islands of active hematopoietic cells scattered in otherwise fatty marrow. MR may prove to be a valuable, noninvasive method of following the response of patients with aplastic anemia to therapy; more investigation is necessary before this can be definitely concluded.

Original languageEnglish (US)
Pages (from-to)441-444
Number of pages4
JournalRadiology
Volume164
Issue number2
DOIs
StatePublished - Jan 1 1987

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Aplastic Anemia
Bone Marrow
Magnetic Resonance Imaging
Pelvis
Femur
Spine
Magnetic Resonance Spectroscopy
Biopsy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Bone marrow patterns in aplastic anemia : Observations with 1.5-T MR imaging. / Kaplan, P. A.; Asleson, R. J.; Klassen, Lynell Warren; Duggan, M. J.

In: Radiology, Vol. 164, No. 2, 01.01.1987, p. 441-444.

Research output: Contribution to journalArticle

Kaplan, P. A. ; Asleson, R. J. ; Klassen, Lynell Warren ; Duggan, M. J. / Bone marrow patterns in aplastic anemia : Observations with 1.5-T MR imaging. In: Radiology. 1987 ; Vol. 164, No. 2. pp. 441-444.
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