Bladder carcinoma with lymphoepithelioma-like differentiation: A report of 9 cases

Sten Holmäng, Göran Borghede, Sonny L. Johansson

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

Purpose: Lymphoepithelioma-like carcinoma of the bladder is rare with only 14 cases reported to date. We report 9 additional cases with long-term follow-up. Materials and Methods: All 713 patients with an initial diagnosis of bladder tumor in western Sweden from 1987 through 1988 were prospectively registered and followed. A clinical and histopathological review was performed on 816 bladder tumors from the files of the oncology department treated between 1962 and 1989. Results: Of 9 patients with stages T2M0-T3M0 cancer treated with locoregional therapy 6 with either pure or predominant lymphoepithelioma-like carcinoma pattern had no evidence of disease after a median observation of 4 years (range 1 to 18) and 3 with focal lymphoepithelioma-like carcinoma pattern died of disease after 9 to 68 months. Conclusions: Lymphoepithelioma-like carcinoma is diagnosed in less advanced stages and has a more favorable long-term prognosis than other types of undifferentiated invasive carcinomas of the bladder. Our data and review of the literature suggest that lymphoepithelioma-like carcinoma should be treated stage by stage like other bladder carcinomas.

Original languageEnglish (US)
Pages (from-to)779-782
Number of pages4
JournalJournal of Urology
Volume159
Issue number3
DOIs
StatePublished - Mar 1998

Fingerprint

Urinary Bladder
Carcinoma
Urinary Bladder Neoplasms
Sweden
Observation
Neoplasms

Keywords

  • Bladder
  • Bladder neoplasms
  • Carcinoma

ASJC Scopus subject areas

  • Urology

Cite this

Bladder carcinoma with lymphoepithelioma-like differentiation : A report of 9 cases. / Holmäng, Sten; Borghede, Göran; Johansson, Sonny L.

In: Journal of Urology, Vol. 159, No. 3, 03.1998, p. 779-782.

Research output: Contribution to journalArticle

Holmäng, Sten ; Borghede, Göran ; Johansson, Sonny L. / Bladder carcinoma with lymphoepithelioma-like differentiation : A report of 9 cases. In: Journal of Urology. 1998 ; Vol. 159, No. 3. pp. 779-782.
@article{524a5dc67de142c6b65161f9b601f76c,
title = "Bladder carcinoma with lymphoepithelioma-like differentiation: A report of 9 cases",
abstract = "Purpose: Lymphoepithelioma-like carcinoma of the bladder is rare with only 14 cases reported to date. We report 9 additional cases with long-term follow-up. Materials and Methods: All 713 patients with an initial diagnosis of bladder tumor in western Sweden from 1987 through 1988 were prospectively registered and followed. A clinical and histopathological review was performed on 816 bladder tumors from the files of the oncology department treated between 1962 and 1989. Results: Of 9 patients with stages T2M0-T3M0 cancer treated with locoregional therapy 6 with either pure or predominant lymphoepithelioma-like carcinoma pattern had no evidence of disease after a median observation of 4 years (range 1 to 18) and 3 with focal lymphoepithelioma-like carcinoma pattern died of disease after 9 to 68 months. Conclusions: Lymphoepithelioma-like carcinoma is diagnosed in less advanced stages and has a more favorable long-term prognosis than other types of undifferentiated invasive carcinomas of the bladder. Our data and review of the literature suggest that lymphoepithelioma-like carcinoma should be treated stage by stage like other bladder carcinomas.",
keywords = "Bladder, Bladder neoplasms, Carcinoma",
author = "Sten Holm{\"a}ng and G{\"o}ran Borghede and Johansson, {Sonny L.}",
year = "1998",
month = "3",
doi = "10.1016/S0022-5347(01)63727-3",
language = "English (US)",
volume = "159",
pages = "779--782",
journal = "Journal of Urology",
issn = "0022-5347",
publisher = "Elsevier Inc.",
number = "3",

}

TY - JOUR

T1 - Bladder carcinoma with lymphoepithelioma-like differentiation

T2 - A report of 9 cases

AU - Holmäng, Sten

AU - Borghede, Göran

AU - Johansson, Sonny L.

PY - 1998/3

Y1 - 1998/3

N2 - Purpose: Lymphoepithelioma-like carcinoma of the bladder is rare with only 14 cases reported to date. We report 9 additional cases with long-term follow-up. Materials and Methods: All 713 patients with an initial diagnosis of bladder tumor in western Sweden from 1987 through 1988 were prospectively registered and followed. A clinical and histopathological review was performed on 816 bladder tumors from the files of the oncology department treated between 1962 and 1989. Results: Of 9 patients with stages T2M0-T3M0 cancer treated with locoregional therapy 6 with either pure or predominant lymphoepithelioma-like carcinoma pattern had no evidence of disease after a median observation of 4 years (range 1 to 18) and 3 with focal lymphoepithelioma-like carcinoma pattern died of disease after 9 to 68 months. Conclusions: Lymphoepithelioma-like carcinoma is diagnosed in less advanced stages and has a more favorable long-term prognosis than other types of undifferentiated invasive carcinomas of the bladder. Our data and review of the literature suggest that lymphoepithelioma-like carcinoma should be treated stage by stage like other bladder carcinomas.

AB - Purpose: Lymphoepithelioma-like carcinoma of the bladder is rare with only 14 cases reported to date. We report 9 additional cases with long-term follow-up. Materials and Methods: All 713 patients with an initial diagnosis of bladder tumor in western Sweden from 1987 through 1988 were prospectively registered and followed. A clinical and histopathological review was performed on 816 bladder tumors from the files of the oncology department treated between 1962 and 1989. Results: Of 9 patients with stages T2M0-T3M0 cancer treated with locoregional therapy 6 with either pure or predominant lymphoepithelioma-like carcinoma pattern had no evidence of disease after a median observation of 4 years (range 1 to 18) and 3 with focal lymphoepithelioma-like carcinoma pattern died of disease after 9 to 68 months. Conclusions: Lymphoepithelioma-like carcinoma is diagnosed in less advanced stages and has a more favorable long-term prognosis than other types of undifferentiated invasive carcinomas of the bladder. Our data and review of the literature suggest that lymphoepithelioma-like carcinoma should be treated stage by stage like other bladder carcinomas.

KW - Bladder

KW - Bladder neoplasms

KW - Carcinoma

UR - http://www.scopus.com/inward/record.url?scp=0344936082&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0344936082&partnerID=8YFLogxK

U2 - 10.1016/S0022-5347(01)63727-3

DO - 10.1016/S0022-5347(01)63727-3

M3 - Article

C2 - 9474147

AN - SCOPUS:0344936082

VL - 159

SP - 779

EP - 782

JO - Journal of Urology

JF - Journal of Urology

SN - 0022-5347

IS - 3

ER -