Abstract
Cardiovascular disease remains the leading cause of death in the world. Cardiac and heart valve tissue engineering in the past decade have made progress to recapitulate the native properties of the heart for cardiac regeneration and repair using a myriad of strategies, including concepts of biomaterials, micro-and nanotechnologies, and decellularization. However, one main obstacle for tissue engineering cardiac tissue is incorporating the complex, heterogeneous micro-and macro-cardiac tissue structures for different cell types to adhere, proliferate, and ultimately repair and remodel damaged tissue. 3D bioprinting has emerged as a strategy to address this challenge by providing the technology to fabricate high-resolution scaffolds with heterogeneous biochemical and mechanical properties. This chapter gives an overview of current strategies and limitations for cardiac and heart valve tissue engineering and the advances made in 3D bioprinting for cardiac repair.
| Original language | English (US) |
|---|---|
| Title of host publication | Essentials of 3D Biofabrication and Translation |
| Publisher | Elsevier Inc. |
| Pages | 351-370 |
| Number of pages | 20 |
| ISBN (Electronic) | 9780128010150 |
| ISBN (Print) | 9780128009727 |
| DOIs | |
| State | Published - Aug 7 2015 |
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Keywords
- 3D printing
- Bioreactor
- Heart valve
- Microfabrication
- Tissue engineering
ASJC Scopus subject areas
- Medicine(all)
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
Bioprinting of cardiac tissues. / Cheung, Daniel Y.C.; Duan, Bin; Butcher, Jonathan T.
Essentials of 3D Biofabrication and Translation. Elsevier Inc., 2015. p. 351-370.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Bioprinting of cardiac tissues
AU - Cheung, Daniel Y.C.
AU - Duan, Bin
AU - Butcher, Jonathan T.
PY - 2015/8/7
Y1 - 2015/8/7
N2 - Cardiovascular disease remains the leading cause of death in the world. Cardiac and heart valve tissue engineering in the past decade have made progress to recapitulate the native properties of the heart for cardiac regeneration and repair using a myriad of strategies, including concepts of biomaterials, micro-and nanotechnologies, and decellularization. However, one main obstacle for tissue engineering cardiac tissue is incorporating the complex, heterogeneous micro-and macro-cardiac tissue structures for different cell types to adhere, proliferate, and ultimately repair and remodel damaged tissue. 3D bioprinting has emerged as a strategy to address this challenge by providing the technology to fabricate high-resolution scaffolds with heterogeneous biochemical and mechanical properties. This chapter gives an overview of current strategies and limitations for cardiac and heart valve tissue engineering and the advances made in 3D bioprinting for cardiac repair.
AB - Cardiovascular disease remains the leading cause of death in the world. Cardiac and heart valve tissue engineering in the past decade have made progress to recapitulate the native properties of the heart for cardiac regeneration and repair using a myriad of strategies, including concepts of biomaterials, micro-and nanotechnologies, and decellularization. However, one main obstacle for tissue engineering cardiac tissue is incorporating the complex, heterogeneous micro-and macro-cardiac tissue structures for different cell types to adhere, proliferate, and ultimately repair and remodel damaged tissue. 3D bioprinting has emerged as a strategy to address this challenge by providing the technology to fabricate high-resolution scaffolds with heterogeneous biochemical and mechanical properties. This chapter gives an overview of current strategies and limitations for cardiac and heart valve tissue engineering and the advances made in 3D bioprinting for cardiac repair.
KW - 3D printing
KW - Bioreactor
KW - Heart valve
KW - Microfabrication
KW - Tissue engineering
UR - http://www.scopus.com/inward/record.url?scp=84940731613&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84940731613&partnerID=8YFLogxK
U2 - 10.1016/B978-0-12-800972-7.00021-9
DO - 10.1016/B978-0-12-800972-7.00021-9
M3 - Chapter
AN - SCOPUS:84940731613
SN - 9780128009727
SP - 351
EP - 370
BT - Essentials of 3D Biofabrication and Translation
PB - Elsevier Inc.
ER -