Biological functions of multistable proteins

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Multistable proteins are defined as those that have available more than one most stable conformation. This capability requires a reversal of the most stable and metastable designations dependent upon environmental conditions. The concept of multistability is discussed with regard to enzyme maturation, hybrid vigor, metabolic temperature compensation, developmental gradients, membrane transport and the classical theory of allostery.

Original languageEnglish (US)
Pages (from-to)507-515
Number of pages9
JournalJournal of Theoretical Biology
Volume40
Issue number3
DOIs
StatePublished - Aug 22 1973

Fingerprint

Hybrid Vigor
heterosis
Conformations
Enzymes
Temperature Compensation
Proteins
Membranes
Protein
Multistability
environmental factors
Temperature
enzymes
Reversal
Conformation
temperature
Membrane
proteins
Gradient
Dependent
Compensation and Redress

ASJC Scopus subject areas

  • Statistics and Probability
  • Medicine(all)
  • Modeling and Simulation
  • Immunology and Microbiology(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • Applied Mathematics

Cite this

Biological functions of multistable proteins. / Nickerson, Kenneth.

In: Journal of Theoretical Biology, Vol. 40, No. 3, 22.08.1973, p. 507-515.

Research output: Contribution to journalArticle

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