Biocompatibility of Te-As-Se glass fibers for cell-based bio-optic infrared sensors

Allison A. Wilhelm, Pierre Lucas, Diana L. DeRosa, Mark Riley

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The chemical stability and toxicity of Te-As-Se (TAS) infrared fibers are investigated. These fibers are used for biosensing applications that involve direct contact with live cultivated human cells. It is shown that TAS fibers exhibit a small oxidation layer after extended exposure to air. This layer is highly soluble in water and easily removed. However, the TAS glass itself is stable in water over several days. While oxidized fibers release arsenate ions, which result in toxic effects to the cells, fresh or washed fibers show no toxic effects. A good correlation is shown between surface etching and the disappearance of toxicity.

Original languageEnglish (US)
Pages (from-to)1098-1104
Number of pages7
JournalJournal of Materials Research
Volume22
Issue number4
DOIs
StatePublished - Apr 1 2007

Fingerprint

biocompatibility
glass fibers
Biocompatibility
Glass fibers
Optics
optics
Infrared radiation
fibers
Fibers
sensors
Sensors
cells
toxicity
Poisons
fiber pullout
Toxicity
arsenates
Water
water
Chemical stability

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Biocompatibility of Te-As-Se glass fibers for cell-based bio-optic infrared sensors. / Wilhelm, Allison A.; Lucas, Pierre; DeRosa, Diana L.; Riley, Mark.

In: Journal of Materials Research, Vol. 22, No. 4, 01.04.2007, p. 1098-1104.

Research output: Contribution to journalArticle

Wilhelm, Allison A. ; Lucas, Pierre ; DeRosa, Diana L. ; Riley, Mark. / Biocompatibility of Te-As-Se glass fibers for cell-based bio-optic infrared sensors. In: Journal of Materials Research. 2007 ; Vol. 22, No. 4. pp. 1098-1104.
@article{2e4ccc27d61b4510b18eaad126626981,
title = "Biocompatibility of Te-As-Se glass fibers for cell-based bio-optic infrared sensors",
abstract = "The chemical stability and toxicity of Te-As-Se (TAS) infrared fibers are investigated. These fibers are used for biosensing applications that involve direct contact with live cultivated human cells. It is shown that TAS fibers exhibit a small oxidation layer after extended exposure to air. This layer is highly soluble in water and easily removed. However, the TAS glass itself is stable in water over several days. While oxidized fibers release arsenate ions, which result in toxic effects to the cells, fresh or washed fibers show no toxic effects. A good correlation is shown between surface etching and the disappearance of toxicity.",
author = "Wilhelm, {Allison A.} and Pierre Lucas and DeRosa, {Diana L.} and Mark Riley",
year = "2007",
month = "4",
day = "1",
doi = "10.1557/jmr.2007.0127",
language = "English (US)",
volume = "22",
pages = "1098--1104",
journal = "Journal of Materials Research",
issn = "0884-2914",
publisher = "Materials Research Society",
number = "4",

}

TY - JOUR

T1 - Biocompatibility of Te-As-Se glass fibers for cell-based bio-optic infrared sensors

AU - Wilhelm, Allison A.

AU - Lucas, Pierre

AU - DeRosa, Diana L.

AU - Riley, Mark

PY - 2007/4/1

Y1 - 2007/4/1

N2 - The chemical stability and toxicity of Te-As-Se (TAS) infrared fibers are investigated. These fibers are used for biosensing applications that involve direct contact with live cultivated human cells. It is shown that TAS fibers exhibit a small oxidation layer after extended exposure to air. This layer is highly soluble in water and easily removed. However, the TAS glass itself is stable in water over several days. While oxidized fibers release arsenate ions, which result in toxic effects to the cells, fresh or washed fibers show no toxic effects. A good correlation is shown between surface etching and the disappearance of toxicity.

AB - The chemical stability and toxicity of Te-As-Se (TAS) infrared fibers are investigated. These fibers are used for biosensing applications that involve direct contact with live cultivated human cells. It is shown that TAS fibers exhibit a small oxidation layer after extended exposure to air. This layer is highly soluble in water and easily removed. However, the TAS glass itself is stable in water over several days. While oxidized fibers release arsenate ions, which result in toxic effects to the cells, fresh or washed fibers show no toxic effects. A good correlation is shown between surface etching and the disappearance of toxicity.

UR - http://www.scopus.com/inward/record.url?scp=34247353198&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34247353198&partnerID=8YFLogxK

U2 - 10.1557/jmr.2007.0127

DO - 10.1557/jmr.2007.0127

M3 - Article

VL - 22

SP - 1098

EP - 1104

JO - Journal of Materials Research

JF - Journal of Materials Research

SN - 0884-2914

IS - 4

ER -