Abstract
The chemical stability and toxicity of Te-As-Se (TAS) infrared fibers are investigated. These fibers are used for biosensing applications that involve direct contact with live cultivated human cells. It is shown that TAS fibers exhibit a small oxidation layer after extended exposure to air. This layer is highly soluble in water and easily removed. However, the TAS glass itself is stable in water over several days. While oxidized fibers release arsenate ions, which result in toxic effects to the cells, fresh or washed fibers show no toxic effects. A good correlation is shown between surface etching and the disappearance of toxicity.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1098-1104 |
| Number of pages | 7 |
| Journal | Journal of Materials Research |
| Volume | 22 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 1 2007 |
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ASJC Scopus subject areas
- Materials Science(all)
- Condensed Matter Physics
- Mechanics of Materials
- Mechanical Engineering
Cite this
Biocompatibility of Te-As-Se glass fibers for cell-based bio-optic infrared sensors. / Wilhelm, Allison A.; Lucas, Pierre; DeRosa, Diana L.; Riley, Mark.
In: Journal of Materials Research, Vol. 22, No. 4, 01.04.2007, p. 1098-1104.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Biocompatibility of Te-As-Se glass fibers for cell-based bio-optic infrared sensors
AU - Wilhelm, Allison A.
AU - Lucas, Pierre
AU - DeRosa, Diana L.
AU - Riley, Mark
PY - 2007/4/1
Y1 - 2007/4/1
N2 - The chemical stability and toxicity of Te-As-Se (TAS) infrared fibers are investigated. These fibers are used for biosensing applications that involve direct contact with live cultivated human cells. It is shown that TAS fibers exhibit a small oxidation layer after extended exposure to air. This layer is highly soluble in water and easily removed. However, the TAS glass itself is stable in water over several days. While oxidized fibers release arsenate ions, which result in toxic effects to the cells, fresh or washed fibers show no toxic effects. A good correlation is shown between surface etching and the disappearance of toxicity.
AB - The chemical stability and toxicity of Te-As-Se (TAS) infrared fibers are investigated. These fibers are used for biosensing applications that involve direct contact with live cultivated human cells. It is shown that TAS fibers exhibit a small oxidation layer after extended exposure to air. This layer is highly soluble in water and easily removed. However, the TAS glass itself is stable in water over several days. While oxidized fibers release arsenate ions, which result in toxic effects to the cells, fresh or washed fibers show no toxic effects. A good correlation is shown between surface etching and the disappearance of toxicity.
UR - http://www.scopus.com/inward/record.url?scp=34247353198&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34247353198&partnerID=8YFLogxK
U2 - 10.1557/jmr.2007.0127
DO - 10.1557/jmr.2007.0127
M3 - Article
VL - 22
SP - 1098
EP - 1104
JO - Journal of Materials Research
JF - Journal of Materials Research
SN - 0884-2914
IS - 4
ER -