Benefits of combined aerobic/resistance/inspiratory training in patients with chronic heart failure. A complete exercise model? A prospective randomised study

Ioannis D. Laoutaris, Stamatis Adamopoulos, Athanassios Manginas, Demosthenes B. Panagiotakos, Manolis S. Kallistratos, Costas Doulaptsis, Alexandros Kouloubinis, Vasilis Voudris, Gregory Pavlides, Dennis V. Cokkinos, Athanasios Dritsas

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Background: We hypothesised that combined aerobic training (AT) with resistance training (RT) and inspiratory muscle training (IMT) could result in additional benefits over AT alone in patients with chronic heart failure (CHF). Methods: Twenty-seven patients, age 58 ± 9 years, NYHA II/III and LVEF 29 ± 7% were randomly assigned to a 12-week AT (n = 14) or a combined AT/RT/IMT (ARIS) (n = 13) exercise program. AT consisted of bike exercise at 70-80% of max heart rate. ARIS training consisted of AT with RT of the quadriceps at 50% of 1 repetition maximum (1RM) and upper limb exercises using dumbbells of 1-2 kg as well as IMT at 60% of sustained maximal inspiratory pressure (SPImax). At baseline and after intervention patients underwent cardiopulmonary exercise testing, echocardiography, evaluation of dyspnea, muscle function and quality of life (QoL) scores. Results: The ARIS program as compared to AT alone, resulted in additional improvement in quadriceps muscle strength (1RM, p = 0.005) and endurance (50%1RM × number of max repetitions, p = 0.01), SPImax (p < 0.001), exercise time (p = 0.01), circulatory power (peak oxygen consumption × peak systolic blood pressure, p = 0.05), dyspnea (p = 0.03) and QoL (p = 0.03). Conclusions: ARIS training was safe and resulted in incremental benefits in both peripheral and respiratory muscle weakness, cardiopulmonary function and QoL compared to that of AT. The present findings may add a new prospective to cardiac rehabilitation programs of heart failure patients whilst the clinical significance of these outcomes need to be addressed in larger randomised studies.

Original languageEnglish (US)
Pages (from-to)1967-1972
Number of pages6
JournalInternational Journal of Cardiology
Volume167
Issue number5
DOIs
StatePublished - Sep 1 2013

Fingerprint

Resistance Training
Heart Failure
Prospective Studies
Exercise
Muscles
Quality of Life
Dyspnea
Blood Pressure
Respiratory Muscles
Muscle Weakness
Quadriceps Muscle
Muscle Strength
Upper Extremity
Oxygen Consumption
Echocardiography
Heart Rate

Keywords

  • Aerobic training
  • Exercise
  • Heart failure
  • Inspiratory muscle training
  • Rehabilitation
  • Resistance training

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Benefits of combined aerobic/resistance/inspiratory training in patients with chronic heart failure. A complete exercise model? A prospective randomised study. / Laoutaris, Ioannis D.; Adamopoulos, Stamatis; Manginas, Athanassios; Panagiotakos, Demosthenes B.; Kallistratos, Manolis S.; Doulaptsis, Costas; Kouloubinis, Alexandros; Voudris, Vasilis; Pavlides, Gregory; Cokkinos, Dennis V.; Dritsas, Athanasios.

In: International Journal of Cardiology, Vol. 167, No. 5, 01.09.2013, p. 1967-1972.

Research output: Contribution to journalArticle

Laoutaris, ID, Adamopoulos, S, Manginas, A, Panagiotakos, DB, Kallistratos, MS, Doulaptsis, C, Kouloubinis, A, Voudris, V, Pavlides, G, Cokkinos, DV & Dritsas, A 2013, 'Benefits of combined aerobic/resistance/inspiratory training in patients with chronic heart failure. A complete exercise model? A prospective randomised study', International Journal of Cardiology, vol. 167, no. 5, pp. 1967-1972. https://doi.org/10.1016/j.ijcard.2012.05.019
Laoutaris, Ioannis D. ; Adamopoulos, Stamatis ; Manginas, Athanassios ; Panagiotakos, Demosthenes B. ; Kallistratos, Manolis S. ; Doulaptsis, Costas ; Kouloubinis, Alexandros ; Voudris, Vasilis ; Pavlides, Gregory ; Cokkinos, Dennis V. ; Dritsas, Athanasios. / Benefits of combined aerobic/resistance/inspiratory training in patients with chronic heart failure. A complete exercise model? A prospective randomised study. In: International Journal of Cardiology. 2013 ; Vol. 167, No. 5. pp. 1967-1972.
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abstract = "Background: We hypothesised that combined aerobic training (AT) with resistance training (RT) and inspiratory muscle training (IMT) could result in additional benefits over AT alone in patients with chronic heart failure (CHF). Methods: Twenty-seven patients, age 58 ± 9 years, NYHA II/III and LVEF 29 ± 7{\%} were randomly assigned to a 12-week AT (n = 14) or a combined AT/RT/IMT (ARIS) (n = 13) exercise program. AT consisted of bike exercise at 70-80{\%} of max heart rate. ARIS training consisted of AT with RT of the quadriceps at 50{\%} of 1 repetition maximum (1RM) and upper limb exercises using dumbbells of 1-2 kg as well as IMT at 60{\%} of sustained maximal inspiratory pressure (SPImax). At baseline and after intervention patients underwent cardiopulmonary exercise testing, echocardiography, evaluation of dyspnea, muscle function and quality of life (QoL) scores. Results: The ARIS program as compared to AT alone, resulted in additional improvement in quadriceps muscle strength (1RM, p = 0.005) and endurance (50{\%}1RM × number of max repetitions, p = 0.01), SPImax (p < 0.001), exercise time (p = 0.01), circulatory power (peak oxygen consumption × peak systolic blood pressure, p = 0.05), dyspnea (p = 0.03) and QoL (p = 0.03). Conclusions: ARIS training was safe and resulted in incremental benefits in both peripheral and respiratory muscle weakness, cardiopulmonary function and QoL compared to that of AT. The present findings may add a new prospective to cardiac rehabilitation programs of heart failure patients whilst the clinical significance of these outcomes need to be addressed in larger randomised studies.",
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AU - Manginas, Athanassios

AU - Panagiotakos, Demosthenes B.

AU - Kallistratos, Manolis S.

AU - Doulaptsis, Costas

AU - Kouloubinis, Alexandros

AU - Voudris, Vasilis

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N2 - Background: We hypothesised that combined aerobic training (AT) with resistance training (RT) and inspiratory muscle training (IMT) could result in additional benefits over AT alone in patients with chronic heart failure (CHF). Methods: Twenty-seven patients, age 58 ± 9 years, NYHA II/III and LVEF 29 ± 7% were randomly assigned to a 12-week AT (n = 14) or a combined AT/RT/IMT (ARIS) (n = 13) exercise program. AT consisted of bike exercise at 70-80% of max heart rate. ARIS training consisted of AT with RT of the quadriceps at 50% of 1 repetition maximum (1RM) and upper limb exercises using dumbbells of 1-2 kg as well as IMT at 60% of sustained maximal inspiratory pressure (SPImax). At baseline and after intervention patients underwent cardiopulmonary exercise testing, echocardiography, evaluation of dyspnea, muscle function and quality of life (QoL) scores. Results: The ARIS program as compared to AT alone, resulted in additional improvement in quadriceps muscle strength (1RM, p = 0.005) and endurance (50%1RM × number of max repetitions, p = 0.01), SPImax (p < 0.001), exercise time (p = 0.01), circulatory power (peak oxygen consumption × peak systolic blood pressure, p = 0.05), dyspnea (p = 0.03) and QoL (p = 0.03). Conclusions: ARIS training was safe and resulted in incremental benefits in both peripheral and respiratory muscle weakness, cardiopulmonary function and QoL compared to that of AT. The present findings may add a new prospective to cardiac rehabilitation programs of heart failure patients whilst the clinical significance of these outcomes need to be addressed in larger randomised studies.

AB - Background: We hypothesised that combined aerobic training (AT) with resistance training (RT) and inspiratory muscle training (IMT) could result in additional benefits over AT alone in patients with chronic heart failure (CHF). Methods: Twenty-seven patients, age 58 ± 9 years, NYHA II/III and LVEF 29 ± 7% were randomly assigned to a 12-week AT (n = 14) or a combined AT/RT/IMT (ARIS) (n = 13) exercise program. AT consisted of bike exercise at 70-80% of max heart rate. ARIS training consisted of AT with RT of the quadriceps at 50% of 1 repetition maximum (1RM) and upper limb exercises using dumbbells of 1-2 kg as well as IMT at 60% of sustained maximal inspiratory pressure (SPImax). At baseline and after intervention patients underwent cardiopulmonary exercise testing, echocardiography, evaluation of dyspnea, muscle function and quality of life (QoL) scores. Results: The ARIS program as compared to AT alone, resulted in additional improvement in quadriceps muscle strength (1RM, p = 0.005) and endurance (50%1RM × number of max repetitions, p = 0.01), SPImax (p < 0.001), exercise time (p = 0.01), circulatory power (peak oxygen consumption × peak systolic blood pressure, p = 0.05), dyspnea (p = 0.03) and QoL (p = 0.03). Conclusions: ARIS training was safe and resulted in incremental benefits in both peripheral and respiratory muscle weakness, cardiopulmonary function and QoL compared to that of AT. The present findings may add a new prospective to cardiac rehabilitation programs of heart failure patients whilst the clinical significance of these outcomes need to be addressed in larger randomised studies.

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