Beef heifers with diminished numbers of antral follicles have decreased uterine protein concentrations

Anthony K. McNeel, Émerson M. Soares, Allyson L. Patterson, Jeffrey L. Vallet, Elane C. Wright, Erin L. Larimore, Olivia L. Amundson, Jeremy R. Miles, Chadwick C. Chase, Clay A. Lents, Jennifer R. Wood, Andrea S. Cupp, George A. Perry, Robert A. Cushman

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Previous research demonstrated a favorable relationship between the number of follicles detectable in the bovine ovary by ultrasonography and fertility, and bovine females with diminished numbers of antral follicles had smaller reproductive tracts. Therefore, we hypothesized that uterine function would be compromised in beef heifers with diminished numbers of antral follilcles. Angus heifers (n = 480) were submitted for ultrasonographic evaluation of antral follicle number at 325 and 355 d of age. After the second ultrasonographic examination, 40 pubertal heifers with the greatest average number of antral follicles (30.9 ± 0.7) and 40 pubertal heifers with the lowest average number of antral follicles (14.2 ± 0.7) were synchronized with two i.m. injections of prostaglandin F (25 mg) administered 11 d apart, and heifers were slaughtered on d 6 (n = 26 heifers/group) or d 16 (n = 14 heifers/group) of the resultant estrous cycle. The uterus was weighed, flushed for determination of protein content, and representative samples were fixed for determination of endometrial gland morphometry. Heifers in the Low group had fewer surface antral follicles and smaller reproductive tracts than heifers in the High group (P < 0.01). Protein content of the uterine flushes was decreased in heifers in the Low group (P < 0.01); however, there was no difference in the percent area of the endometrium occupied by endometrial glands. From these results, we conclude that the uterine environment of beef heifers with diminished numbers of antral follicles is less conducive to supporting early embryonic survival.

Original languageEnglish (US)
Pages (from-to)1-9
Number of pages9
JournalAnimal Reproduction Science
Volume179
DOIs
StatePublished - Apr 1 2017

Fingerprint

beef cattle
heifers
Proteins
proteins
Dinoprost
Estrous Cycle
protein content
Endometrium
Antral
Uterus
Fertility
cattle
endometrium
Ovary
Ultrasonography
Angus
morphometry
estrous cycle
ultrasonography
uterus

Keywords

  • Fertility
  • Ovarian reserve
  • Uterus

ASJC Scopus subject areas

  • Food Animals
  • Animal Science and Zoology
  • Endocrinology

Cite this

McNeel, A. K., Soares, É. M., Patterson, A. L., Vallet, J. L., Wright, E. C., Larimore, E. L., ... Cushman, R. A. (2017). Beef heifers with diminished numbers of antral follicles have decreased uterine protein concentrations. Animal Reproduction Science, 179, 1-9. https://doi.org/10.1016/j.anireprosci.2017.01.004

Beef heifers with diminished numbers of antral follicles have decreased uterine protein concentrations. / McNeel, Anthony K.; Soares, Émerson M.; Patterson, Allyson L.; Vallet, Jeffrey L.; Wright, Elane C.; Larimore, Erin L.; Amundson, Olivia L.; Miles, Jeremy R.; Chase, Chadwick C.; Lents, Clay A.; Wood, Jennifer R.; Cupp, Andrea S.; Perry, George A.; Cushman, Robert A.

In: Animal Reproduction Science, Vol. 179, 01.04.2017, p. 1-9.

Research output: Contribution to journalArticle

McNeel, AK, Soares, ÉM, Patterson, AL, Vallet, JL, Wright, EC, Larimore, EL, Amundson, OL, Miles, JR, Chase, CC, Lents, CA, Wood, JR, Cupp, AS, Perry, GA & Cushman, RA 2017, 'Beef heifers with diminished numbers of antral follicles have decreased uterine protein concentrations', Animal Reproduction Science, vol. 179, pp. 1-9. https://doi.org/10.1016/j.anireprosci.2017.01.004
McNeel, Anthony K. ; Soares, Émerson M. ; Patterson, Allyson L. ; Vallet, Jeffrey L. ; Wright, Elane C. ; Larimore, Erin L. ; Amundson, Olivia L. ; Miles, Jeremy R. ; Chase, Chadwick C. ; Lents, Clay A. ; Wood, Jennifer R. ; Cupp, Andrea S. ; Perry, George A. ; Cushman, Robert A. / Beef heifers with diminished numbers of antral follicles have decreased uterine protein concentrations. In: Animal Reproduction Science. 2017 ; Vol. 179. pp. 1-9.
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