Bacteriology of the paranasal sinuses in pediatric cystic fibrosis patients

G. Paul Digoy, Joel D. Dunn, Julie A. Stoner, Alana Christie, Dwight T. Jones

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Objectives: To review the characteristic microbiology of the paranasal sinuses in patients with cystic fibrosis who undergo endoscopic sinus surgery. To examine the subtypes of organisms cultured from the maxillary sinuses and determine their sensitivity to antibiotic therapy. Study design: Retrospective chart review. Setting: Tertiary care children's hospital. Methods: Sinus cultures were obtained from 51 patients with cystic fibrosis during endoscopic sinus procedures between 2000 and 2004 at a tertiary care children's hospital. A retrospective chart review was undertaken to obtain culture and sensitivity data of the sinus contents. Results: The most common bacteria isolated was Staphylococcus aureus (71%), followed by Pseudomonas aeruginosa (PSA) (27%), Haemophilus influenzae (21%), Staphylococcus non-aureus (16%) and Streptococcus viridans (12%). Streptococcus pneumoniae and Moraxella catarrhalis were rarely isolated (2% and 0% respectively). Twenty-nine percent of the patients with cultures positive for PSA were of the mucoid variant. Only one patient had culture positive Escherichia coli. Antibiotic resistance among the more common organisms cultured from the sinus samples is also listed. Conclusion: Staph. aureus is the most common isolate in the sinuses of this pediatric CF population followed by P. aeruginosa and H. influenzae. Although many isolates are pansensitive, some isolates are panresistant.

Original languageEnglish (US)
Pages (from-to)934-938
Number of pages5
JournalInternational Journal of Pediatric Otorhinolaryngology
Volume76
Issue number7
DOIs
Publication statusPublished - Jul 1 2012

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Keywords

  • Clindamycin
  • MRSA
  • Neck abscess
  • Pediatric

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Otorhinolaryngology

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