Bacteriology of the paranasal sinuses in pediatric cystic fibrosis patients

G. Paul Digoy, Joel D. Dunn, Julie A. Stoner, Alana Christie, Dwight T. Jones

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Objectives: To review the characteristic microbiology of the paranasal sinuses in patients with cystic fibrosis who undergo endoscopic sinus surgery. To examine the subtypes of organisms cultured from the maxillary sinuses and determine their sensitivity to antibiotic therapy. Study design: Retrospective chart review. Setting: Tertiary care children's hospital. Methods: Sinus cultures were obtained from 51 patients with cystic fibrosis during endoscopic sinus procedures between 2000 and 2004 at a tertiary care children's hospital. A retrospective chart review was undertaken to obtain culture and sensitivity data of the sinus contents. Results: The most common bacteria isolated was Staphylococcus aureus (71%), followed by Pseudomonas aeruginosa (PSA) (27%), Haemophilus influenzae (21%), Staphylococcus non-aureus (16%) and Streptococcus viridans (12%). Streptococcus pneumoniae and Moraxella catarrhalis were rarely isolated (2% and 0% respectively). Twenty-nine percent of the patients with cultures positive for PSA were of the mucoid variant. Only one patient had culture positive Escherichia coli. Antibiotic resistance among the more common organisms cultured from the sinus samples is also listed. Conclusion: Staph. aureus is the most common isolate in the sinuses of this pediatric CF population followed by P. aeruginosa and H. influenzae. Although many isolates are pansensitive, some isolates are panresistant.

Original languageEnglish (US)
Pages (from-to)934-938
Number of pages5
JournalInternational Journal of Pediatric Otorhinolaryngology
Volume76
Issue number7
DOIs
StatePublished - Jul 1 2012

Fingerprint

Bacteriology
Paranasal Sinuses
Cystic Fibrosis
Pseudomonas aeruginosa
Pediatrics
Haemophilus influenzae
Tertiary Healthcare
Staphylococcus aureus
Viridans Streptococci
Moraxella (Branhamella) catarrhalis
Maxillary Sinus
Microbial Drug Resistance
Streptococcus pneumoniae
Microbiology
Retrospective Studies
Escherichia coli
Anti-Bacterial Agents
Bacteria
Population
Therapeutics

Keywords

  • Clindamycin
  • MRSA
  • Neck abscess
  • Pediatric

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Otorhinolaryngology

Cite this

Bacteriology of the paranasal sinuses in pediatric cystic fibrosis patients. / Digoy, G. Paul; Dunn, Joel D.; Stoner, Julie A.; Christie, Alana; Jones, Dwight T.

In: International Journal of Pediatric Otorhinolaryngology, Vol. 76, No. 7, 01.07.2012, p. 934-938.

Research output: Contribution to journalArticle

Digoy, G. Paul ; Dunn, Joel D. ; Stoner, Julie A. ; Christie, Alana ; Jones, Dwight T. / Bacteriology of the paranasal sinuses in pediatric cystic fibrosis patients. In: International Journal of Pediatric Otorhinolaryngology. 2012 ; Vol. 76, No. 7. pp. 934-938.
@article{03485d410f5b4abf8f2ac031704df2c5,
title = "Bacteriology of the paranasal sinuses in pediatric cystic fibrosis patients",
abstract = "Objectives: To review the characteristic microbiology of the paranasal sinuses in patients with cystic fibrosis who undergo endoscopic sinus surgery. To examine the subtypes of organisms cultured from the maxillary sinuses and determine their sensitivity to antibiotic therapy. Study design: Retrospective chart review. Setting: Tertiary care children's hospital. Methods: Sinus cultures were obtained from 51 patients with cystic fibrosis during endoscopic sinus procedures between 2000 and 2004 at a tertiary care children's hospital. A retrospective chart review was undertaken to obtain culture and sensitivity data of the sinus contents. Results: The most common bacteria isolated was Staphylococcus aureus (71{\%}), followed by Pseudomonas aeruginosa (PSA) (27{\%}), Haemophilus influenzae (21{\%}), Staphylococcus non-aureus (16{\%}) and Streptococcus viridans (12{\%}). Streptococcus pneumoniae and Moraxella catarrhalis were rarely isolated (2{\%} and 0{\%} respectively). Twenty-nine percent of the patients with cultures positive for PSA were of the mucoid variant. Only one patient had culture positive Escherichia coli. Antibiotic resistance among the more common organisms cultured from the sinus samples is also listed. Conclusion: Staph. aureus is the most common isolate in the sinuses of this pediatric CF population followed by P. aeruginosa and H. influenzae. Although many isolates are pansensitive, some isolates are panresistant.",
keywords = "Clindamycin, MRSA, Neck abscess, Pediatric",
author = "Digoy, {G. Paul} and Dunn, {Joel D.} and Stoner, {Julie A.} and Alana Christie and Jones, {Dwight T.}",
year = "2012",
month = "7",
day = "1",
doi = "10.1016/j.ijporl.2012.02.043",
language = "English (US)",
volume = "76",
pages = "934--938",
journal = "International Journal of Pediatric Otorhinolaryngology",
issn = "0165-5876",
publisher = "Elsevier Ireland Ltd",
number = "7",

}

TY - JOUR

T1 - Bacteriology of the paranasal sinuses in pediatric cystic fibrosis patients

AU - Digoy, G. Paul

AU - Dunn, Joel D.

AU - Stoner, Julie A.

AU - Christie, Alana

AU - Jones, Dwight T.

PY - 2012/7/1

Y1 - 2012/7/1

N2 - Objectives: To review the characteristic microbiology of the paranasal sinuses in patients with cystic fibrosis who undergo endoscopic sinus surgery. To examine the subtypes of organisms cultured from the maxillary sinuses and determine their sensitivity to antibiotic therapy. Study design: Retrospective chart review. Setting: Tertiary care children's hospital. Methods: Sinus cultures were obtained from 51 patients with cystic fibrosis during endoscopic sinus procedures between 2000 and 2004 at a tertiary care children's hospital. A retrospective chart review was undertaken to obtain culture and sensitivity data of the sinus contents. Results: The most common bacteria isolated was Staphylococcus aureus (71%), followed by Pseudomonas aeruginosa (PSA) (27%), Haemophilus influenzae (21%), Staphylococcus non-aureus (16%) and Streptococcus viridans (12%). Streptococcus pneumoniae and Moraxella catarrhalis were rarely isolated (2% and 0% respectively). Twenty-nine percent of the patients with cultures positive for PSA were of the mucoid variant. Only one patient had culture positive Escherichia coli. Antibiotic resistance among the more common organisms cultured from the sinus samples is also listed. Conclusion: Staph. aureus is the most common isolate in the sinuses of this pediatric CF population followed by P. aeruginosa and H. influenzae. Although many isolates are pansensitive, some isolates are panresistant.

AB - Objectives: To review the characteristic microbiology of the paranasal sinuses in patients with cystic fibrosis who undergo endoscopic sinus surgery. To examine the subtypes of organisms cultured from the maxillary sinuses and determine their sensitivity to antibiotic therapy. Study design: Retrospective chart review. Setting: Tertiary care children's hospital. Methods: Sinus cultures were obtained from 51 patients with cystic fibrosis during endoscopic sinus procedures between 2000 and 2004 at a tertiary care children's hospital. A retrospective chart review was undertaken to obtain culture and sensitivity data of the sinus contents. Results: The most common bacteria isolated was Staphylococcus aureus (71%), followed by Pseudomonas aeruginosa (PSA) (27%), Haemophilus influenzae (21%), Staphylococcus non-aureus (16%) and Streptococcus viridans (12%). Streptococcus pneumoniae and Moraxella catarrhalis were rarely isolated (2% and 0% respectively). Twenty-nine percent of the patients with cultures positive for PSA were of the mucoid variant. Only one patient had culture positive Escherichia coli. Antibiotic resistance among the more common organisms cultured from the sinus samples is also listed. Conclusion: Staph. aureus is the most common isolate in the sinuses of this pediatric CF population followed by P. aeruginosa and H. influenzae. Although many isolates are pansensitive, some isolates are panresistant.

KW - Clindamycin

KW - MRSA

KW - Neck abscess

KW - Pediatric

UR - http://www.scopus.com/inward/record.url?scp=84861939078&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84861939078&partnerID=8YFLogxK

U2 - 10.1016/j.ijporl.2012.02.043

DO - 10.1016/j.ijporl.2012.02.043

M3 - Article

C2 - 22513080

AN - SCOPUS:84861939078

VL - 76

SP - 934

EP - 938

JO - International Journal of Pediatric Otorhinolaryngology

JF - International Journal of Pediatric Otorhinolaryngology

SN - 0165-5876

IS - 7

ER -