Bacterial mutagenicity of extracts of the baked and raw Agaricus bisporus mushroom

B. Toth, P. Gannett, Eleanor G Rogan, J. Williamson

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Aqueous extracts of baked and raw Agericus bisporus (AB) mushroom were tested for mutagenic activity in Salmonella typhimurium strains TA1535 and TA1537. The extracts were studied with and without metabolic activation by Aroclor-induced rat liver S9 mix. The extracts of the baked and raw AB exhibited a dose related mutagenic activity with and without activation in strain TA1535. Similar findings were obtained in strain TA1537, although the net revertant values were of lower magnitude. Because humans mainly consume the cultivated mushroom AB in baked form, the implications of the findings are self-evident.

Original languageEnglish (US)
Pages (from-to)487-490
Number of pages4
JournalIn Vivo
Volume6
Issue number5
StatePublished - Jan 1 1992

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Agaricus
Agaricales
Aroclors
Salmonella typhimurium
Chemical activation
Salmonella
Liver
Rats
Metabolic Activation

Keywords

  • cancer
  • diet
  • hydrazines
  • mushroom
  • mutagenesis

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology

Cite this

Bacterial mutagenicity of extracts of the baked and raw Agaricus bisporus mushroom. / Toth, B.; Gannett, P.; Rogan, Eleanor G; Williamson, J.

In: In Vivo, Vol. 6, No. 5, 01.01.1992, p. 487-490.

Research output: Contribution to journalArticle

Toth, B, Gannett, P, Rogan, EG & Williamson, J 1992, 'Bacterial mutagenicity of extracts of the baked and raw Agaricus bisporus mushroom', In Vivo, vol. 6, no. 5, pp. 487-490.
Toth, B. ; Gannett, P. ; Rogan, Eleanor G ; Williamson, J. / Bacterial mutagenicity of extracts of the baked and raw Agaricus bisporus mushroom. In: In Vivo. 1992 ; Vol. 6, No. 5. pp. 487-490.
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