Autologous intestinal reconstruction surgery for intestinal failure management

Brian A. Jones, Melissa A. Hull, Heung Bae Kim

Research output: Contribution to journalReview article

14 Scopus citations

Abstract

PURPOSE OF REVIEW: Multidisciplinary management of intestinal failure has progressed over the past 30 years, facilitating the transition to enteral autonomy in many pediatric patients. However, there remains a select group of patients who reach a plateau in advancement of their enteral nutrition. Numerous surgical options have been pursued to attempt to slow intestinal transit, taper dilated bowel, and promote intestinal adaptation. This review highlights the current literature on autologous intestinal reconstruction surgery, focusing on the two most commonly performed procedures, the longitudinal intestinal lengthening and tailoring (LILT) and serial transverse enteroplasty (STEP). RECENT FINDINGS: LILT and STEP remain viable options to treat medically refractory short bowel syndrome. There is over 20 years of experience with the LILT procedure in the literature, with one large series showing that 67% of patients eventually transitioned to full enteral nutrition. The International STEP Data Registry reported a weaning rate of 34% after median follow-up of 12.6 months. Repeat STEP has been described as a possible treatment for the redilation that occurs after both LILT and STEP. SUMMARY: LILT and STEP may facilitate enteral feeding advancement in patients with medically refractory short bowel syndrome

Original languageEnglish (US)
Pages (from-to)341-345
Number of pages5
JournalCurrent opinion in organ transplantation
Volume15
Issue number3
DOIs
Publication statusPublished - Jun 1 2010

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Keywords

  • Autologous intestinal reconstruction surgery
  • Longitudinal intestinal lengthening and tailoring
  • Serial transverse enteroplasty

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation

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