Asymmetric Catalysis Using Self-Assembled Chiral Bidentate P,P-Ligands

James M Takacs, D. Sahadeva Reddy, Shin A. Moteki, Di Wu, Hector Palencia

Research output: Contribution to journalArticle

149 Citations (Scopus)

Abstract

A strategy is described for modular catalyst development based upon metal-directed self-assembly of bifunctional subunits around a structural metal to form a heteroleptic complex in which a second set of ligating groups are now suitably disposed to bind a second metal to form a catalytic site. A library of chiral diphosphites was prepared via metal-directed self-assembly and used in a simple asymmetric allylic amination, giving enantiomeric excesses as high as 97%.

Original languageEnglish (US)
Pages (from-to)4494-4495
Number of pages2
JournalJournal of the American Chemical Society
Volume126
Issue number14
DOIs
StatePublished - Apr 14 2004

Fingerprint

Catalysis
Metals
Ligands
Self assembly
Structural metals
Amination
Libraries
Catalytic Domain
Catalysts

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

Asymmetric Catalysis Using Self-Assembled Chiral Bidentate P,P-Ligands. / Takacs, James M; Reddy, D. Sahadeva; Moteki, Shin A.; Wu, Di; Palencia, Hector.

In: Journal of the American Chemical Society, Vol. 126, No. 14, 14.04.2004, p. 4494-4495.

Research output: Contribution to journalArticle

Takacs, James M ; Reddy, D. Sahadeva ; Moteki, Shin A. ; Wu, Di ; Palencia, Hector. / Asymmetric Catalysis Using Self-Assembled Chiral Bidentate P,P-Ligands. In: Journal of the American Chemical Society. 2004 ; Vol. 126, No. 14. pp. 4494-4495.
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