Assessment of urinary protein excretion in the adolescent: Effect of body position and exercise

Mark T. Houser, Mary Frances Jahn, Ailan Kobayashi, John Norman Walburn

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Abstract

We examined the effects of body position and exercise on the random urinary protein/creatinine ratio (Up/Ucr) in healthy adolescents, to provide reference data to be used in a simplified evaluation of proteinuria. Random urine samples were obtained during recumbency and after both ambulation and exercise in 116 subjects. The Up/Ucr was significantly (P<0.0001) higher with increasing levels of activity, and was widely variable, especially during the upright and postexercise periods. No sex-reiated differences in Up/Ucr were noted, except during recumbency, when values were significantly (P<0.001) higher in females. The urinary dipstick was found to be less sensitive as a tool to define abnormal degrees of recumbent proteinuria. We conclude that body position and exercise have significant effects on protein excretion, and suggest that the Up/Ucr in recumbent and upright urine samples will be useful in the evaluation of proteinuria.

Original languageEnglish (US)
Pages (from-to)556-561
Number of pages6
JournalThe Journal of Pediatrics
Volume109
Issue number3
DOIs
Publication statusPublished - Sep 1986

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ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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