Assessment of papillary muscle function using myocardial velocity gradient derived from tissue Doppler echocardiography

Banthit Khankirawatana, Suwanee Khankirawatana, Heidi Mahrous, Thomas Richard Porter

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Papillary muscle (PM) function is vital to mitral valve competence. However, quantitative assessment of the function is difficult due to the complexity of the mitral apparatus. We hypothesized that myocardial velocity gradient (MVG) could be applied to assess PM function. We studied MVG-PM in 123 patients with left ventricular dysfunction (ejection fraction <40%) and 123 normal subjects throughout a systolic phase. MVG-PM in normal subjects was significantly higher than in patients with left ventricular dysfunction (3.6/s vs 1.4/s, p <0.001). MVG-PM reached its peak at early systole and correlated well with PM thickening (r = 0.89). MVG-PM in patients with left ventricular dysfunction correlated with the severity of apical tenting of the mitral valve (y = 0.8x - 0.07, r = 0.72). Patients with lower MVG-PM tended to have less severe mitral regurgitation (y = 0.03x + 0.3, r = 0.83). PM contractility can be quantitatively assessed by calculating the MVG derived from tissue Doppler imaging. PM dysfunction, indicated by lower MVG-PM, decreased mitral leaflet tethering, thus paradoxically decreasing mitral regurgitation severity. MVG is a useful tool in determining the role of PM in functional mitral regurgitation.

Original languageEnglish (US)
Pages (from-to)45-49
Number of pages5
JournalAmerican Journal of Cardiology
Volume94
Issue number1
DOIs
StatePublished - Jul 1 2004

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Papillary Muscles
Doppler Echocardiography
Mitral Valve Insufficiency
Left Ventricular Dysfunction
Mitral Valve
Systole
Stroke Volume
Mental Competency

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Assessment of papillary muscle function using myocardial velocity gradient derived from tissue Doppler echocardiography. / Khankirawatana, Banthit; Khankirawatana, Suwanee; Mahrous, Heidi; Porter, Thomas Richard.

In: American Journal of Cardiology, Vol. 94, No. 1, 01.07.2004, p. 45-49.

Research output: Contribution to journalArticle

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