Approximate entropy values demonstrate impaired neuromotor control of spontaneous leg activity in infants with myelomeningocele

Beth A. Smith, Caroline Teulier, Jennifer Sansom, Nicholas Stergiou, Beverly D. Ulrich

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Purpose: One obstacle to providing early intervention to infants with myelomeningocele (MMC) is the challenge of quantifying impaired neuromotor control of movements early in life. Methods: We used the nonlinear analysis tool Approximate Entropy (ApEn) to analyze periodicity and complexity of supine spontaneous lower extremity movements of infants with MMC and typical development (TD) at 1, 3, 6, and 9 months of age. Results: Movements of infants with MMC were more regular and repeatable (lower ApEn values) than movements of infants with TD, indicating less adaptive and flexible movement patterns. For both groups ApEn values decreased with age, and the movements of infants with MMC were less complex than movements of infants with TD. Further, for infants with MMC, lesion level and age of walking onset correlated negatively with ApEn values. Conclusions: Our study begins to demonstrate the feasibility of ApEn to identify impaired neuromotor control in infants with MMC.

Original languageEnglish (US)
Pages (from-to)241-247
Number of pages7
JournalPediatric Physical Therapy
Volume23
Issue number3
DOIs
StatePublished - Sep 1 2011

Fingerprint

Meningomyelocele
Entropy
Leg
Periodicity
Systems Analysis
Age of Onset
Walking
Lower Extremity

Keywords

  • entropy
  • infants
  • leg
  • motor activity
  • myelomeningocele
  • nervous system/growth and development
  • psychomotor performance/physiology

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Approximate entropy values demonstrate impaired neuromotor control of spontaneous leg activity in infants with myelomeningocele. / Smith, Beth A.; Teulier, Caroline; Sansom, Jennifer; Stergiou, Nicholas; Ulrich, Beverly D.

In: Pediatric Physical Therapy, Vol. 23, No. 3, 01.09.2011, p. 241-247.

Research output: Contribution to journalArticle

Smith, Beth A. ; Teulier, Caroline ; Sansom, Jennifer ; Stergiou, Nicholas ; Ulrich, Beverly D. / Approximate entropy values demonstrate impaired neuromotor control of spontaneous leg activity in infants with myelomeningocele. In: Pediatric Physical Therapy. 2011 ; Vol. 23, No. 3. pp. 241-247.
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