Application of image-guided surface coil P-31 MR spectroscopy to human liver, heart, and kidney

G. B. Matson, D. B. Twieg, G. S. Karczmar, T. J. Lawry, J. R. Gober, M. Valenza, M. D. Boska, M. W. Weiner

Research output: Contribution to journalArticle

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Abstract

Localized phosphorus-31 magnetic resonance (MR) spectroscopy in humans has previously been accomplished with surface coils by means of depth-resolved surface coil spectroscopy or rotating frame experiments in which the extent of tissue sampled critically depends on surface coil placement. The authors' goal was to modify the surface coil image-selected in vivo spectroscopy (ISIS) experiment to accomplish thee-dimensional volume selection through application of selective pulses in the presence of B 0 gradients. Advantages of ISIS include the ability to use proton images to define the volume of interest (VOI) and reduced dependence on exact positioning of the surface coil. However, rapid replication of the surface coil ISIS experiment can cause spectral contamination from signals originating outside the VOI. A modified version of the ISIS experiment was developed to alleviate contamination under conditions of rapid replication. Applications of localized P-31 MR spectroscopy for observation of high-energy phosphorus metabolites are presented in human liver, heart, and transplanted and normal kidney.

Original languageEnglish (US)
Pages (from-to)541-547
Number of pages7
JournalRadiology
Volume169
Issue number2
DOIs
StatePublished - Jan 1 1988

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Spectrum Analysis
Magnetic Resonance Spectroscopy
Kidney
Liver
Phosphorus
Protons
Observation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Matson, G. B., Twieg, D. B., Karczmar, G. S., Lawry, T. J., Gober, J. R., Valenza, M., ... Weiner, M. W. (1988). Application of image-guided surface coil P-31 MR spectroscopy to human liver, heart, and kidney. Radiology, 169(2), 541-547. https://doi.org/10.1148/radiology.169.2.3051120

Application of image-guided surface coil P-31 MR spectroscopy to human liver, heart, and kidney. / Matson, G. B.; Twieg, D. B.; Karczmar, G. S.; Lawry, T. J.; Gober, J. R.; Valenza, M.; Boska, M. D.; Weiner, M. W.

In: Radiology, Vol. 169, No. 2, 01.01.1988, p. 541-547.

Research output: Contribution to journalArticle

Matson, GB, Twieg, DB, Karczmar, GS, Lawry, TJ, Gober, JR, Valenza, M, Boska, MD & Weiner, MW 1988, 'Application of image-guided surface coil P-31 MR spectroscopy to human liver, heart, and kidney', Radiology, vol. 169, no. 2, pp. 541-547. https://doi.org/10.1148/radiology.169.2.3051120
Matson GB, Twieg DB, Karczmar GS, Lawry TJ, Gober JR, Valenza M et al. Application of image-guided surface coil P-31 MR spectroscopy to human liver, heart, and kidney. Radiology. 1988 Jan 1;169(2):541-547. https://doi.org/10.1148/radiology.169.2.3051120
Matson, G. B. ; Twieg, D. B. ; Karczmar, G. S. ; Lawry, T. J. ; Gober, J. R. ; Valenza, M. ; Boska, M. D. ; Weiner, M. W. / Application of image-guided surface coil P-31 MR spectroscopy to human liver, heart, and kidney. In: Radiology. 1988 ; Vol. 169, No. 2. pp. 541-547.
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