Antimicrobial stewardship in outpatient settings: leveraging innovative physician-pharmacist collaborations to reduce antibiotic resistance

Michael E. Klepser, Alex J. Adams, Donald G. Klepser

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Antibiotic resistance is one of the world's most pressing public health problems. Historically, most drug-resistant bacteria have emerged in hospital settings, yet the vast majority of antimicrobials used in humans in the United States are administered in outpatient settings. Strong collaboration between physicians and pharmacists in the development of antimicrobial stewardship programs in outpatient settings is thus a critical strategy for curtailing antibiotic resistance. Recently, pilot projects have been launched in 3 states that pair physicians and community pharmacists under a Collaborative Practice Agreement (CPA) to treat patients with influenza and group A Streptococcus (GAS) pharyngitis. Under this model, community pharmacists use rapid point-of-care tests to guide clinical decision making and initiate treatment as appropriate under a physician-led, evidence-based protocol. Experience with this research initiative has suggested this model can lead to more judicious use of antibiotics and antivirals, improve public health, and provide safe and convenient care for patients.

Original languageEnglish (US)
Pages (from-to)166-173
Number of pages8
JournalHealth Security
Volume13
Issue number3
DOIs
StatePublished - May 1 2015

Fingerprint

antibiotic resistance
pharmacist
Antibiotics
Microbial Drug Resistance
Pharmacists
public health
Outpatients
physician
Public health
Physicians
influenza
Public Health
Point-of-Care Systems
antibiotics
drug
Pharyngitis
decision making
pilot project
Medical problems
Streptococcus

ASJC Scopus subject areas

  • Health(social science)
  • Emergency Medicine
  • Safety Research
  • Public Health, Environmental and Occupational Health
  • Management, Monitoring, Policy and Law
  • Health, Toxicology and Mutagenesis

Cite this

Antimicrobial stewardship in outpatient settings : leveraging innovative physician-pharmacist collaborations to reduce antibiotic resistance. / Klepser, Michael E.; Adams, Alex J.; Klepser, Donald G.

In: Health Security, Vol. 13, No. 3, 01.05.2015, p. 166-173.

Research output: Contribution to journalArticle

@article{96342dc5f40447bc9c1b1433e59fcf7c,
title = "Antimicrobial stewardship in outpatient settings: leveraging innovative physician-pharmacist collaborations to reduce antibiotic resistance",
abstract = "Antibiotic resistance is one of the world's most pressing public health problems. Historically, most drug-resistant bacteria have emerged in hospital settings, yet the vast majority of antimicrobials used in humans in the United States are administered in outpatient settings. Strong collaboration between physicians and pharmacists in the development of antimicrobial stewardship programs in outpatient settings is thus a critical strategy for curtailing antibiotic resistance. Recently, pilot projects have been launched in 3 states that pair physicians and community pharmacists under a Collaborative Practice Agreement (CPA) to treat patients with influenza and group A Streptococcus (GAS) pharyngitis. Under this model, community pharmacists use rapid point-of-care tests to guide clinical decision making and initiate treatment as appropriate under a physician-led, evidence-based protocol. Experience with this research initiative has suggested this model can lead to more judicious use of antibiotics and antivirals, improve public health, and provide safe and convenient care for patients.",
author = "Klepser, {Michael E.} and Adams, {Alex J.} and Klepser, {Donald G.}",
year = "2015",
month = "5",
day = "1",
doi = "10.1089/hs.2014.0083",
language = "English (US)",
volume = "13",
pages = "166--173",
journal = "Health security",
issn = "2326-5094",
publisher = "Mary Ann Liebert Inc.",
number = "3",

}

TY - JOUR

T1 - Antimicrobial stewardship in outpatient settings

T2 - leveraging innovative physician-pharmacist collaborations to reduce antibiotic resistance

AU - Klepser, Michael E.

AU - Adams, Alex J.

AU - Klepser, Donald G.

PY - 2015/5/1

Y1 - 2015/5/1

N2 - Antibiotic resistance is one of the world's most pressing public health problems. Historically, most drug-resistant bacteria have emerged in hospital settings, yet the vast majority of antimicrobials used in humans in the United States are administered in outpatient settings. Strong collaboration between physicians and pharmacists in the development of antimicrobial stewardship programs in outpatient settings is thus a critical strategy for curtailing antibiotic resistance. Recently, pilot projects have been launched in 3 states that pair physicians and community pharmacists under a Collaborative Practice Agreement (CPA) to treat patients with influenza and group A Streptococcus (GAS) pharyngitis. Under this model, community pharmacists use rapid point-of-care tests to guide clinical decision making and initiate treatment as appropriate under a physician-led, evidence-based protocol. Experience with this research initiative has suggested this model can lead to more judicious use of antibiotics and antivirals, improve public health, and provide safe and convenient care for patients.

AB - Antibiotic resistance is one of the world's most pressing public health problems. Historically, most drug-resistant bacteria have emerged in hospital settings, yet the vast majority of antimicrobials used in humans in the United States are administered in outpatient settings. Strong collaboration between physicians and pharmacists in the development of antimicrobial stewardship programs in outpatient settings is thus a critical strategy for curtailing antibiotic resistance. Recently, pilot projects have been launched in 3 states that pair physicians and community pharmacists under a Collaborative Practice Agreement (CPA) to treat patients with influenza and group A Streptococcus (GAS) pharyngitis. Under this model, community pharmacists use rapid point-of-care tests to guide clinical decision making and initiate treatment as appropriate under a physician-led, evidence-based protocol. Experience with this research initiative has suggested this model can lead to more judicious use of antibiotics and antivirals, improve public health, and provide safe and convenient care for patients.

UR - http://www.scopus.com/inward/record.url?scp=84991211998&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84991211998&partnerID=8YFLogxK

U2 - 10.1089/hs.2014.0083

DO - 10.1089/hs.2014.0083

M3 - Article

C2 - 26042860

AN - SCOPUS:84991211998

VL - 13

SP - 166

EP - 173

JO - Health security

JF - Health security

SN - 2326-5094

IS - 3

ER -