Antidepressants in the treatment of depression in older adults

Prasad R. Padala, William H. Roccaforte, William J. Burke

Research output: Contribution to journalReview article

1 Scopus citations


Depression in the elderly is a common problem that is often underdiagnosed and undertreated. Late-life depression is associated with significant medical and psychiatric morbidity and mortality, including suicide. Antidepressant medications play a vital role in the treatment of late-life depression, along with nonpharmacologic treatments, such as psychotherapy and electroconvulsive therapy. Evidence suggests that all the available antidepressants are equally efficacious. Selection of an agent is usually made after considering safety, tolerability, and the presence of other medical conditions. Most older patients can be treated safely and effectively, and sustained remission with minimal residual symptoms should be the goal of treatment.

Original languageEnglish (US)
Pages (from-to)35-39
Number of pages5
JournalPrimary Psychiatry
Issue number8
Publication statusPublished - Aug 1 2004


ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Padala, P. R., Roccaforte, W. H., & Burke, W. J. (2004). Antidepressants in the treatment of depression in older adults. Primary Psychiatry, 11(8), 35-39.