Antibacterial activity of Pyrrosia petiolosa ethyl acetate extract against Staphylococcus aureus by decreasing hla and sea virulence genes

Liju Song, Mei Cao, Chong Chen, Panpan Qi, Ningzhe Li, Daoyan Wu, Jingshan Peng, Xuege Wang, Mao Zhang, Guoku Hu, Jian Zhao

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The aim of this study was to explore the antibacterial activity of Pyrrosia petiolosa ethyl acetate extract (PPEAE) against Staphylococcus aureus in vitro and analyse its chemical components by gas chromatograph-mass spectrometry. The results of anti-microbial assay revealed that PPEAE had strong inhibitory activity against S.aureus, with MIC and MBC of 7.8 and 15.6 mg/mL, respectively. The transcriptional levels of hla and sea were reduced to 14.33 and 46.39% at the MIC compared to the control. Analysing test result exhibited that eugenol made a great contribution to antibacterial activity. This experiment indicated that PPEAE had prominent antibacterial activity against S. aureus.

Original languageEnglish (US)
Pages (from-to)1347-1350
Number of pages4
JournalNatural Product Research
Volume31
Issue number11
DOIs
StatePublished - Jun 3 2017

Fingerprint

Pyrrosia
Oceans and Seas
Virulence
Staphylococcus aureus
virulence
Genes
extracts
Eugenol
genes
eugenol
Mass spectrometry
Assays
Mass Spectrometry
Gases
gases
mass spectrometry
assays
ethyl acetate
Experiments
testing

Keywords

  • antibacterial activity
  • composition analysis
  • Pyrrosia petiolosa ethyl acetate extract (PPEAE)
  • Staphylococcus aureus

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Plant Science
  • Organic Chemistry

Cite this

Antibacterial activity of Pyrrosia petiolosa ethyl acetate extract against Staphylococcus aureus by decreasing hla and sea virulence genes. / Song, Liju; Cao, Mei; Chen, Chong; Qi, Panpan; Li, Ningzhe; Wu, Daoyan; Peng, Jingshan; Wang, Xuege; Zhang, Mao; Hu, Guoku; Zhao, Jian.

In: Natural Product Research, Vol. 31, No. 11, 03.06.2017, p. 1347-1350.

Research output: Contribution to journalArticle

Song, Liju ; Cao, Mei ; Chen, Chong ; Qi, Panpan ; Li, Ningzhe ; Wu, Daoyan ; Peng, Jingshan ; Wang, Xuege ; Zhang, Mao ; Hu, Guoku ; Zhao, Jian. / Antibacterial activity of Pyrrosia petiolosa ethyl acetate extract against Staphylococcus aureus by decreasing hla and sea virulence genes. In: Natural Product Research. 2017 ; Vol. 31, No. 11. pp. 1347-1350.
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