Androgen-dependent peptides of the rat ventral prostate nuclear envelope

Jaya T. Venkatraman, Gillian M Howell, Yvonne A. Lefebvre

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Nuclear envelope peptides of the rat ventral prostate in the molecular weight region 18,400 to 19,400 show marked androgen dependence. After castration these peptides disappear. Re-administration of testosterone restores them. They were not extracted by 0.1 M NaCl or 5% HClO4 but were partially extracted by 0.35 M NaCl and 1% Triton. These peptides were not present in rat liver nuclear envelopes. As these androgen-dependent non-histone peptides have similar characteristics to androgen-dependent peptides identified in the prostate nucleus, we conclude that the nuclear peptides are at least partially localized to the nuclear envelope.

Original languageEnglish (US)
Pages (from-to)469-474
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume125
Issue number2
DOIs
StatePublished - Dec 14 1984

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Nuclear Envelope
Androgens
Rats
Prostate
Peptides
Castration
Liver
Testosterone
Molecular Weight
Molecular weight

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

Cite this

Androgen-dependent peptides of the rat ventral prostate nuclear envelope. / Venkatraman, Jaya T.; Howell, Gillian M; Lefebvre, Yvonne A.

In: Biochemical and Biophysical Research Communications, Vol. 125, No. 2, 14.12.1984, p. 469-474.

Research output: Contribution to journalArticle

Venkatraman, Jaya T. ; Howell, Gillian M ; Lefebvre, Yvonne A. / Androgen-dependent peptides of the rat ventral prostate nuclear envelope. In: Biochemical and Biophysical Research Communications. 1984 ; Vol. 125, No. 2. pp. 469-474.
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