An integrated multipurpose lesion-making electrode

Matthew A. Howard, Lori K. Reed, Roman Mirsky, Bruce A. Abkes, Igor O. Volkov

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

PURPOSE: Although excellent results are reported from centers using microelectrode mapping during stereotactic pallidotomy, the recording methods used are time-consuming and technically cumbersome. We sought to develop a new electrode concept that may, when eventually applied in clinical practice, improve the efficiency and safety of microelectrode-guided functional neurosurgical procedures. CONCEPT: The scout electrode uses a recently developed research technique for simultaneously obtaining multiple microelectrode recordings along the shaft of a macroelectrode. RATIONALE: By positioning recording sites on either side of a lesion-making contact, it is possible to functionally 'scout' the brain tissue surrounding the proposed lesion site, thus eliminating the need for serial movements and electrode interchanges. DISCUSSION: The feasibility of the scout electrode concept was tested using prototypes placed into cat medial geniculate nucleus. High- quality unit recordings were simultaneously obtained from different regions within the medial geniculate nucleus. This ability to physiologically map sites above and below the lesion-making contact facilitated precise placement of radiofrequency lesions in the center of the medial geniculate nucleus. These results suggest that it may be possible to develop clinically useful devices based on this novel concept.

Original languageEnglish (US)
Pages (from-to)137-142
Number of pages6
JournalNeurosurgery
Volume42
Issue number1
DOIs
StatePublished - Jan 1 1998

Fingerprint

Geniculate Bodies
Electrodes
Microelectrodes
Pallidotomy
Neurosurgical Procedures
Cats
Research Design
Safety
Equipment and Supplies
Brain

Keywords

  • Action potentials
  • Electrode
  • Microelectrode
  • Pallidotomy
  • RF lesion

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Howard, M. A., Reed, L. K., Mirsky, R., Abkes, B. A., & Volkov, I. O. (1998). An integrated multipurpose lesion-making electrode. Neurosurgery, 42(1), 137-142. https://doi.org/10.1097/00006123-199801000-00029

An integrated multipurpose lesion-making electrode. / Howard, Matthew A.; Reed, Lori K.; Mirsky, Roman; Abkes, Bruce A.; Volkov, Igor O.

In: Neurosurgery, Vol. 42, No. 1, 01.01.1998, p. 137-142.

Research output: Contribution to journalArticle

Howard, MA, Reed, LK, Mirsky, R, Abkes, BA & Volkov, IO 1998, 'An integrated multipurpose lesion-making electrode', Neurosurgery, vol. 42, no. 1, pp. 137-142. https://doi.org/10.1097/00006123-199801000-00029
Howard MA, Reed LK, Mirsky R, Abkes BA, Volkov IO. An integrated multipurpose lesion-making electrode. Neurosurgery. 1998 Jan 1;42(1):137-142. https://doi.org/10.1097/00006123-199801000-00029
Howard, Matthew A. ; Reed, Lori K. ; Mirsky, Roman ; Abkes, Bruce A. ; Volkov, Igor O. / An integrated multipurpose lesion-making electrode. In: Neurosurgery. 1998 ; Vol. 42, No. 1. pp. 137-142.
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