An evaluation of the darkroom prone provocative test in family members of primary angle closure glaucoma patients

R. Sihota, S. Mohan, T. Dada, V. Gupta, R. M. Pandey, D. Ghate

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Purpose: To compare ocular biometric parameters with darkroom prone provocative test (DRPPT) in family members of primary angle closure glaucoma (PACG) patients. Methods: One hundred and forty-nine family members of 46 PACG patients underwent ocular examination included slit lamp biomicroscopy, gonioscopy, fundus examination using +90 D lens, Goldmann applanation tonometry, darkroom prone provocative test, perimetry on Humphrey's field analyzer II and optic disc evaluation using HRT II. Ultrasonic ocular biometry and the DRPPT were then performed. IOP≥ 8 mmHg rise from baseline with iridocorneal touch was considered as a positive test. Results: Of the 149 family members examined, 55 (36.9%) were found to have PACG. Forty (72.7%) of these had subacute PACG and 15 (27.3%) were found to have chronic PACG. Thirty-nine (70.3%) of the affected members showed a positive DRPPT. Mean anterior chamber depth (ACD) was 2.03±0.3, 2.3±0.4, 2.7±0.3 mm (P = 0.0001) and mean lens thickness was 4.41±0.39, 3.99±0.5, 3.93±0.4 mm (P = 0.0001) in DRPPT positives, borderlines and negatives respectively. ROC curve (ACD) plotted showed cutoff value of 2.07 mm (sensitivity 88.57%) for screening. Conclusion: Anterior chamber is shallowest, lensis thickest and axial length is shortest in affected and DRPPT positive, family members of PACG patients.

Original languageEnglish (US)
Pages (from-to)984-989
Number of pages6
JournalEye
Volume21
Issue number7
DOIs
StatePublished - Jul 2007

Fingerprint

Angle Closure Glaucoma
Anterior Chamber
Lenses
Gonioscopy
Biometry
Visual Field Tests
Optic Disk
Manometry
Touch
Ultrasonics
ROC Curve

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems

Cite this

An evaluation of the darkroom prone provocative test in family members of primary angle closure glaucoma patients. / Sihota, R.; Mohan, S.; Dada, T.; Gupta, V.; Pandey, R. M.; Ghate, D.

In: Eye, Vol. 21, No. 7, 07.2007, p. 984-989.

Research output: Contribution to journalArticle

Sihota, R. ; Mohan, S. ; Dada, T. ; Gupta, V. ; Pandey, R. M. ; Ghate, D. / An evaluation of the darkroom prone provocative test in family members of primary angle closure glaucoma patients. In: Eye. 2007 ; Vol. 21, No. 7. pp. 984-989.
@article{c1162f5386f34d8194cfcdda1c73ac4f,
title = "An evaluation of the darkroom prone provocative test in family members of primary angle closure glaucoma patients",
abstract = "Purpose: To compare ocular biometric parameters with darkroom prone provocative test (DRPPT) in family members of primary angle closure glaucoma (PACG) patients. Methods: One hundred and forty-nine family members of 46 PACG patients underwent ocular examination included slit lamp biomicroscopy, gonioscopy, fundus examination using +90 D lens, Goldmann applanation tonometry, darkroom prone provocative test, perimetry on Humphrey's field analyzer II and optic disc evaluation using HRT II. Ultrasonic ocular biometry and the DRPPT were then performed. IOP≥ 8 mmHg rise from baseline with iridocorneal touch was considered as a positive test. Results: Of the 149 family members examined, 55 (36.9{\%}) were found to have PACG. Forty (72.7{\%}) of these had subacute PACG and 15 (27.3{\%}) were found to have chronic PACG. Thirty-nine (70.3{\%}) of the affected members showed a positive DRPPT. Mean anterior chamber depth (ACD) was 2.03±0.3, 2.3±0.4, 2.7±0.3 mm (P = 0.0001) and mean lens thickness was 4.41±0.39, 3.99±0.5, 3.93±0.4 mm (P = 0.0001) in DRPPT positives, borderlines and negatives respectively. ROC curve (ACD) plotted showed cutoff value of 2.07 mm (sensitivity 88.57{\%}) for screening. Conclusion: Anterior chamber is shallowest, lensis thickest and axial length is shortest in affected and DRPPT positive, family members of PACG patients.",
author = "R. Sihota and S. Mohan and T. Dada and V. Gupta and Pandey, {R. M.} and D. Ghate",
year = "2007",
month = "7",
doi = "10.1038/sj.eye.6702375",
language = "English (US)",
volume = "21",
pages = "984--989",
journal = "Eye (London, England)",
issn = "0950-222X",
publisher = "Nature Publishing Group",
number = "7",

}

TY - JOUR

T1 - An evaluation of the darkroom prone provocative test in family members of primary angle closure glaucoma patients

AU - Sihota, R.

AU - Mohan, S.

AU - Dada, T.

AU - Gupta, V.

AU - Pandey, R. M.

AU - Ghate, D.

PY - 2007/7

Y1 - 2007/7

N2 - Purpose: To compare ocular biometric parameters with darkroom prone provocative test (DRPPT) in family members of primary angle closure glaucoma (PACG) patients. Methods: One hundred and forty-nine family members of 46 PACG patients underwent ocular examination included slit lamp biomicroscopy, gonioscopy, fundus examination using +90 D lens, Goldmann applanation tonometry, darkroom prone provocative test, perimetry on Humphrey's field analyzer II and optic disc evaluation using HRT II. Ultrasonic ocular biometry and the DRPPT were then performed. IOP≥ 8 mmHg rise from baseline with iridocorneal touch was considered as a positive test. Results: Of the 149 family members examined, 55 (36.9%) were found to have PACG. Forty (72.7%) of these had subacute PACG and 15 (27.3%) were found to have chronic PACG. Thirty-nine (70.3%) of the affected members showed a positive DRPPT. Mean anterior chamber depth (ACD) was 2.03±0.3, 2.3±0.4, 2.7±0.3 mm (P = 0.0001) and mean lens thickness was 4.41±0.39, 3.99±0.5, 3.93±0.4 mm (P = 0.0001) in DRPPT positives, borderlines and negatives respectively. ROC curve (ACD) plotted showed cutoff value of 2.07 mm (sensitivity 88.57%) for screening. Conclusion: Anterior chamber is shallowest, lensis thickest and axial length is shortest in affected and DRPPT positive, family members of PACG patients.

AB - Purpose: To compare ocular biometric parameters with darkroom prone provocative test (DRPPT) in family members of primary angle closure glaucoma (PACG) patients. Methods: One hundred and forty-nine family members of 46 PACG patients underwent ocular examination included slit lamp biomicroscopy, gonioscopy, fundus examination using +90 D lens, Goldmann applanation tonometry, darkroom prone provocative test, perimetry on Humphrey's field analyzer II and optic disc evaluation using HRT II. Ultrasonic ocular biometry and the DRPPT were then performed. IOP≥ 8 mmHg rise from baseline with iridocorneal touch was considered as a positive test. Results: Of the 149 family members examined, 55 (36.9%) were found to have PACG. Forty (72.7%) of these had subacute PACG and 15 (27.3%) were found to have chronic PACG. Thirty-nine (70.3%) of the affected members showed a positive DRPPT. Mean anterior chamber depth (ACD) was 2.03±0.3, 2.3±0.4, 2.7±0.3 mm (P = 0.0001) and mean lens thickness was 4.41±0.39, 3.99±0.5, 3.93±0.4 mm (P = 0.0001) in DRPPT positives, borderlines and negatives respectively. ROC curve (ACD) plotted showed cutoff value of 2.07 mm (sensitivity 88.57%) for screening. Conclusion: Anterior chamber is shallowest, lensis thickest and axial length is shortest in affected and DRPPT positive, family members of PACG patients.

UR - http://www.scopus.com/inward/record.url?scp=34447341695&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34447341695&partnerID=8YFLogxK

U2 - 10.1038/sj.eye.6702375

DO - 10.1038/sj.eye.6702375

M3 - Article

C2 - 16710437

AN - SCOPUS:34447341695

VL - 21

SP - 984

EP - 989

JO - Eye (London, England)

JF - Eye (London, England)

SN - 0950-222X

IS - 7

ER -