American Society of Echocardiography Consensus Statement on the Clinical Applications of Ultrasonic Contrast Agents in Echocardiography

Sharon L. Mulvagh, Harry Rakowski, Mani A. Vannan, Sahar S. Abdelmoneim, Harald Becher, S. Michelle Bierig, Peter N. Burns, Ramon Castello, Patrick D. Coon, Mary E. Hagen, James G. Jollis, Thomas R. Kimball, Dalane W. Kitzman, Itzhak Kronzon, Arthur J. Labovitz, Roberto M. Lang, Joseph Mathew, W. Stuart Moir, Sherif F. Nagueh, Alan S. PearlmanJulio E. Perez, Thomas Richard Porter, Judy Rosenbloom, G. Monet Strachan, Srihari Thanigaraj, Kevin Wei, Anna Woo, Eric H C Yu, William A. Zoghbi

Research output: Contribution to journalReview article

299 Citations (Scopus)

Abstract

Continuing Medical Education Course for "American Society of Echocardiography Consensus Statement on the Clinical Applications of Ultrasonic Contrast Agents in Echocardiography". Accreditation Statement: The American Society of Echocardiography (ASE) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The ASE designates this educational activity for a maximum of 1 AMA PRA Category 1 Credit.™ Physicians should only claim credit commensurate with the extent of their participation in the activity. The American Registry of Diagnostic Medical Sonographers and Cardiovascular Credentialing International recognize the ASE's certificates and have agreed to honor the credit hours toward their registry requirements for sonographers. The ASE is committed to resolving all conflict-of-interest issues, and its mandate is to retain only those speakers with financial interests that can be reconciled with the goals and educational integrity of the educational program. Disclosure of faculty and commercial support sponsor relationships, if any, have been indicated. Target Audience: This activity is designed for all cardiovascular physicians, cardiac sonographers, and nurses with a primary interest and knowledge base in the field of echocardiography; in addition, residents, researchers, clinicians, sonographers, and other medical professionals having a specific interest in contrast echocardiography may be included. Objectives: Upon completing this activity, participants will be able to: 1. Demonstrate an increased knowledge of the applications for contrast echocardiography and their impact on cardiac diagnosis. 2. Differentiate the available ultrasound contrast agents and ultrasound equipment imaging features to optimize their use. 3. Recognize the indications, benefits, and safety of ultrasound contrast agents, acknowledging the recent labeling changes by the US Food and Drug Administration (FDA) regarding contrast agent use and safety information. 4. Identify specific patient populations that represent potential candidates for the use of contrast agents, to enable cost-effective clinical diagnosis. 5. Incorporate effective teamwork strategies for the implementation of contrast agents in the echocardiography laboratory and establish guidelines for contrast use. 6. Use contrast enhancement for endocardial border delineation and left ventricular opacification in rest and stress echocardiography and unique patient care environments in which echocardiographic image acquisition is frequently challenging, including intensive care units (ICUs) and emergency departments. 7. Effectively use contrast echocardiography for the diagnosis of intracardiac and extracardiac abnormalities, including the identification of complications of acute myocardial infarction. 8. Assess the common pitfalls in contrast imaging and use stepwise, guideline-based contrast equipment setup and contrast agent administration techniques to optimize image acquisition. Author Disclosures: Sharon L. Mulvagh: research grant, Lantheus Medical Imaging, GE Healthcare, and Astellas Pharma; consultant/advisory, Acusphere, Point Biomedical. Mani A. Vannan: research grant, other research support, speaker bureau/honoraria, and consultant/advisory board, Lantheus Medical Imaging. Harald Becher: research grant, Philips, Sonosite, and Toshiba; speaker bureau/honoraria, Lantheus Medical Imaging; consultant/advisory board, Point Biomedical, Bracco, Acusphere, ICON, Lantheus Medical Imaging. S. Michelle Bierig: research grant, Lantheus Medical Imaging, Amersham. Peter N. Burns: consultant/advisory board, Philips Ultrasound, Lantheus Medical Imaging. Dalane W. Kitzman: research grant, Lantheus Medical Imaging, IMCOR, Sonus; speakers bureau, Lantheus Medical Imaging; consultant/advisory board, Lantheus Medical Imaging, Acusphere. Itzhak Kronzon: research grant, GE Healthcare. Arthur J. Labovitz: consultant/advisory board, ICON Medical. Roberto M. Lang: research grant, Acusphere, Point Biomedical; speaker bureau, Lantheus Medical Imaging; consultant/advisory board, Lantheus Medical Imaging. Julio E. Perez: consultant/advisory board, Biomedical Systems. Thomas R. Porter: research grant, Lantheus Medical Imaging; consultant/advisory board, Acusphere, ImaRx. Judy Rosenbloom: paid consultant with ultrasound equipment manufacturers. Kevin Wei: research grant, Lantheus Medical Imaging, Philips Ultrasound; consultant/advisory board, Acusphere. The following stated no disclosures: Harry Rakowski, Sahar S. Abdelmoneim, Ramon Castello, Patrick D. Coon, Mary E. Hagen, James G. Jollis, Thomas R. Kimball, Joseph Mathew, Stuart Moir, Sherif F. Nagueh, Alan S. Pearlman, G. Monet Strachan, Srihari Thanigaraj, Anna Woo, Eric H. C. Yu, and William A. Zoghbi. Conflicts of Interest: The authors have no conflicts of interest to disclose except as noted above. Estimated Time to Complete This Activity: 1 hour.

Original languageEnglish (US)
Pages (from-to)1179-1201
Number of pages23
JournalJournal of the American Society of Echocardiography
Volume21
Issue number11
DOIs
StatePublished - Nov 1 2008

Fingerprint

Diagnostic Imaging
Ultrasonics
Contrast Media
Echocardiography
Consultants
Consensus
Organized Financing
Research
Conflict of Interest
Continuing Medical Education
Disclosure
Accreditation
Physicians
Equipment and Supplies
Registries
Guidelines
Credentialing
Delivery of Health Care
Safety
Stress Echocardiography

Keywords

  • Cardiac imaging
  • Contrast echocardiography
  • Contrast microbubbles
  • Coronary artery disease
  • Echocardiography
  • Endocardial border definition
  • Left ventricular ejection fraction
  • Left ventricular opacification
  • Myocardial contrast echocardiography
  • Myocardial perfusion imaging
  • Power Doppler imaging
  • Real-time contrast echocardiography
  • Stress echocardiography
  • Ultrasound contrast agents
  • Wall motion analysis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

American Society of Echocardiography Consensus Statement on the Clinical Applications of Ultrasonic Contrast Agents in Echocardiography. / Mulvagh, Sharon L.; Rakowski, Harry; Vannan, Mani A.; Abdelmoneim, Sahar S.; Becher, Harald; Bierig, S. Michelle; Burns, Peter N.; Castello, Ramon; Coon, Patrick D.; Hagen, Mary E.; Jollis, James G.; Kimball, Thomas R.; Kitzman, Dalane W.; Kronzon, Itzhak; Labovitz, Arthur J.; Lang, Roberto M.; Mathew, Joseph; Moir, W. Stuart; Nagueh, Sherif F.; Pearlman, Alan S.; Perez, Julio E.; Porter, Thomas Richard; Rosenbloom, Judy; Strachan, G. Monet; Thanigaraj, Srihari; Wei, Kevin; Woo, Anna; Yu, Eric H C; Zoghbi, William A.

In: Journal of the American Society of Echocardiography, Vol. 21, No. 11, 01.11.2008, p. 1179-1201.

Research output: Contribution to journalReview article

Mulvagh, SL, Rakowski, H, Vannan, MA, Abdelmoneim, SS, Becher, H, Bierig, SM, Burns, PN, Castello, R, Coon, PD, Hagen, ME, Jollis, JG, Kimball, TR, Kitzman, DW, Kronzon, I, Labovitz, AJ, Lang, RM, Mathew, J, Moir, WS, Nagueh, SF, Pearlman, AS, Perez, JE, Porter, TR, Rosenbloom, J, Strachan, GM, Thanigaraj, S, Wei, K, Woo, A, Yu, EHC & Zoghbi, WA 2008, 'American Society of Echocardiography Consensus Statement on the Clinical Applications of Ultrasonic Contrast Agents in Echocardiography', Journal of the American Society of Echocardiography, vol. 21, no. 11, pp. 1179-1201. https://doi.org/10.1016/j.echo.2008.09.009
Mulvagh, Sharon L. ; Rakowski, Harry ; Vannan, Mani A. ; Abdelmoneim, Sahar S. ; Becher, Harald ; Bierig, S. Michelle ; Burns, Peter N. ; Castello, Ramon ; Coon, Patrick D. ; Hagen, Mary E. ; Jollis, James G. ; Kimball, Thomas R. ; Kitzman, Dalane W. ; Kronzon, Itzhak ; Labovitz, Arthur J. ; Lang, Roberto M. ; Mathew, Joseph ; Moir, W. Stuart ; Nagueh, Sherif F. ; Pearlman, Alan S. ; Perez, Julio E. ; Porter, Thomas Richard ; Rosenbloom, Judy ; Strachan, G. Monet ; Thanigaraj, Srihari ; Wei, Kevin ; Woo, Anna ; Yu, Eric H C ; Zoghbi, William A. / American Society of Echocardiography Consensus Statement on the Clinical Applications of Ultrasonic Contrast Agents in Echocardiography. In: Journal of the American Society of Echocardiography. 2008 ; Vol. 21, No. 11. pp. 1179-1201.
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keywords = "Cardiac imaging, Contrast echocardiography, Contrast microbubbles, Coronary artery disease, Echocardiography, Endocardial border definition, Left ventricular ejection fraction, Left ventricular opacification, Myocardial contrast echocardiography, Myocardial perfusion imaging, Power Doppler imaging, Real-time contrast echocardiography, Stress echocardiography, Ultrasound contrast agents, Wall motion analysis",
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TY - JOUR

T1 - American Society of Echocardiography Consensus Statement on the Clinical Applications of Ultrasonic Contrast Agents in Echocardiography

AU - Mulvagh, Sharon L.

AU - Rakowski, Harry

AU - Vannan, Mani A.

AU - Abdelmoneim, Sahar S.

AU - Becher, Harald

AU - Bierig, S. Michelle

AU - Burns, Peter N.

AU - Castello, Ramon

AU - Coon, Patrick D.

AU - Hagen, Mary E.

AU - Jollis, James G.

AU - Kimball, Thomas R.

AU - Kitzman, Dalane W.

AU - Kronzon, Itzhak

AU - Labovitz, Arthur J.

AU - Lang, Roberto M.

AU - Mathew, Joseph

AU - Moir, W. Stuart

AU - Nagueh, Sherif F.

AU - Pearlman, Alan S.

AU - Perez, Julio E.

AU - Porter, Thomas Richard

AU - Rosenbloom, Judy

AU - Strachan, G. Monet

AU - Thanigaraj, Srihari

AU - Wei, Kevin

AU - Woo, Anna

AU - Yu, Eric H C

AU - Zoghbi, William A.

PY - 2008/11/1

Y1 - 2008/11/1

N2 - Continuing Medical Education Course for "American Society of Echocardiography Consensus Statement on the Clinical Applications of Ultrasonic Contrast Agents in Echocardiography". Accreditation Statement: The American Society of Echocardiography (ASE) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The ASE designates this educational activity for a maximum of 1 AMA PRA Category 1 Credit.™ Physicians should only claim credit commensurate with the extent of their participation in the activity. The American Registry of Diagnostic Medical Sonographers and Cardiovascular Credentialing International recognize the ASE's certificates and have agreed to honor the credit hours toward their registry requirements for sonographers. The ASE is committed to resolving all conflict-of-interest issues, and its mandate is to retain only those speakers with financial interests that can be reconciled with the goals and educational integrity of the educational program. Disclosure of faculty and commercial support sponsor relationships, if any, have been indicated. Target Audience: This activity is designed for all cardiovascular physicians, cardiac sonographers, and nurses with a primary interest and knowledge base in the field of echocardiography; in addition, residents, researchers, clinicians, sonographers, and other medical professionals having a specific interest in contrast echocardiography may be included. Objectives: Upon completing this activity, participants will be able to: 1. Demonstrate an increased knowledge of the applications for contrast echocardiography and their impact on cardiac diagnosis. 2. Differentiate the available ultrasound contrast agents and ultrasound equipment imaging features to optimize their use. 3. Recognize the indications, benefits, and safety of ultrasound contrast agents, acknowledging the recent labeling changes by the US Food and Drug Administration (FDA) regarding contrast agent use and safety information. 4. Identify specific patient populations that represent potential candidates for the use of contrast agents, to enable cost-effective clinical diagnosis. 5. Incorporate effective teamwork strategies for the implementation of contrast agents in the echocardiography laboratory and establish guidelines for contrast use. 6. Use contrast enhancement for endocardial border delineation and left ventricular opacification in rest and stress echocardiography and unique patient care environments in which echocardiographic image acquisition is frequently challenging, including intensive care units (ICUs) and emergency departments. 7. Effectively use contrast echocardiography for the diagnosis of intracardiac and extracardiac abnormalities, including the identification of complications of acute myocardial infarction. 8. Assess the common pitfalls in contrast imaging and use stepwise, guideline-based contrast equipment setup and contrast agent administration techniques to optimize image acquisition. Author Disclosures: Sharon L. Mulvagh: research grant, Lantheus Medical Imaging, GE Healthcare, and Astellas Pharma; consultant/advisory, Acusphere, Point Biomedical. Mani A. Vannan: research grant, other research support, speaker bureau/honoraria, and consultant/advisory board, Lantheus Medical Imaging. Harald Becher: research grant, Philips, Sonosite, and Toshiba; speaker bureau/honoraria, Lantheus Medical Imaging; consultant/advisory board, Point Biomedical, Bracco, Acusphere, ICON, Lantheus Medical Imaging. S. Michelle Bierig: research grant, Lantheus Medical Imaging, Amersham. Peter N. Burns: consultant/advisory board, Philips Ultrasound, Lantheus Medical Imaging. Dalane W. Kitzman: research grant, Lantheus Medical Imaging, IMCOR, Sonus; speakers bureau, Lantheus Medical Imaging; consultant/advisory board, Lantheus Medical Imaging, Acusphere. Itzhak Kronzon: research grant, GE Healthcare. Arthur J. Labovitz: consultant/advisory board, ICON Medical. Roberto M. Lang: research grant, Acusphere, Point Biomedical; speaker bureau, Lantheus Medical Imaging; consultant/advisory board, Lantheus Medical Imaging. Julio E. Perez: consultant/advisory board, Biomedical Systems. Thomas R. Porter: research grant, Lantheus Medical Imaging; consultant/advisory board, Acusphere, ImaRx. Judy Rosenbloom: paid consultant with ultrasound equipment manufacturers. Kevin Wei: research grant, Lantheus Medical Imaging, Philips Ultrasound; consultant/advisory board, Acusphere. The following stated no disclosures: Harry Rakowski, Sahar S. Abdelmoneim, Ramon Castello, Patrick D. Coon, Mary E. Hagen, James G. Jollis, Thomas R. Kimball, Joseph Mathew, Stuart Moir, Sherif F. Nagueh, Alan S. Pearlman, G. Monet Strachan, Srihari Thanigaraj, Anna Woo, Eric H. C. Yu, and William A. Zoghbi. Conflicts of Interest: The authors have no conflicts of interest to disclose except as noted above. Estimated Time to Complete This Activity: 1 hour.

AB - Continuing Medical Education Course for "American Society of Echocardiography Consensus Statement on the Clinical Applications of Ultrasonic Contrast Agents in Echocardiography". Accreditation Statement: The American Society of Echocardiography (ASE) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The ASE designates this educational activity for a maximum of 1 AMA PRA Category 1 Credit.™ Physicians should only claim credit commensurate with the extent of their participation in the activity. The American Registry of Diagnostic Medical Sonographers and Cardiovascular Credentialing International recognize the ASE's certificates and have agreed to honor the credit hours toward their registry requirements for sonographers. The ASE is committed to resolving all conflict-of-interest issues, and its mandate is to retain only those speakers with financial interests that can be reconciled with the goals and educational integrity of the educational program. Disclosure of faculty and commercial support sponsor relationships, if any, have been indicated. Target Audience: This activity is designed for all cardiovascular physicians, cardiac sonographers, and nurses with a primary interest and knowledge base in the field of echocardiography; in addition, residents, researchers, clinicians, sonographers, and other medical professionals having a specific interest in contrast echocardiography may be included. Objectives: Upon completing this activity, participants will be able to: 1. Demonstrate an increased knowledge of the applications for contrast echocardiography and their impact on cardiac diagnosis. 2. Differentiate the available ultrasound contrast agents and ultrasound equipment imaging features to optimize their use. 3. Recognize the indications, benefits, and safety of ultrasound contrast agents, acknowledging the recent labeling changes by the US Food and Drug Administration (FDA) regarding contrast agent use and safety information. 4. Identify specific patient populations that represent potential candidates for the use of contrast agents, to enable cost-effective clinical diagnosis. 5. Incorporate effective teamwork strategies for the implementation of contrast agents in the echocardiography laboratory and establish guidelines for contrast use. 6. Use contrast enhancement for endocardial border delineation and left ventricular opacification in rest and stress echocardiography and unique patient care environments in which echocardiographic image acquisition is frequently challenging, including intensive care units (ICUs) and emergency departments. 7. Effectively use contrast echocardiography for the diagnosis of intracardiac and extracardiac abnormalities, including the identification of complications of acute myocardial infarction. 8. Assess the common pitfalls in contrast imaging and use stepwise, guideline-based contrast equipment setup and contrast agent administration techniques to optimize image acquisition. Author Disclosures: Sharon L. Mulvagh: research grant, Lantheus Medical Imaging, GE Healthcare, and Astellas Pharma; consultant/advisory, Acusphere, Point Biomedical. Mani A. Vannan: research grant, other research support, speaker bureau/honoraria, and consultant/advisory board, Lantheus Medical Imaging. Harald Becher: research grant, Philips, Sonosite, and Toshiba; speaker bureau/honoraria, Lantheus Medical Imaging; consultant/advisory board, Point Biomedical, Bracco, Acusphere, ICON, Lantheus Medical Imaging. S. Michelle Bierig: research grant, Lantheus Medical Imaging, Amersham. Peter N. Burns: consultant/advisory board, Philips Ultrasound, Lantheus Medical Imaging. Dalane W. Kitzman: research grant, Lantheus Medical Imaging, IMCOR, Sonus; speakers bureau, Lantheus Medical Imaging; consultant/advisory board, Lantheus Medical Imaging, Acusphere. Itzhak Kronzon: research grant, GE Healthcare. Arthur J. Labovitz: consultant/advisory board, ICON Medical. Roberto M. Lang: research grant, Acusphere, Point Biomedical; speaker bureau, Lantheus Medical Imaging; consultant/advisory board, Lantheus Medical Imaging. Julio E. Perez: consultant/advisory board, Biomedical Systems. Thomas R. Porter: research grant, Lantheus Medical Imaging; consultant/advisory board, Acusphere, ImaRx. Judy Rosenbloom: paid consultant with ultrasound equipment manufacturers. Kevin Wei: research grant, Lantheus Medical Imaging, Philips Ultrasound; consultant/advisory board, Acusphere. The following stated no disclosures: Harry Rakowski, Sahar S. Abdelmoneim, Ramon Castello, Patrick D. Coon, Mary E. Hagen, James G. Jollis, Thomas R. Kimball, Joseph Mathew, Stuart Moir, Sherif F. Nagueh, Alan S. Pearlman, G. Monet Strachan, Srihari Thanigaraj, Anna Woo, Eric H. C. Yu, and William A. Zoghbi. Conflicts of Interest: The authors have no conflicts of interest to disclose except as noted above. Estimated Time to Complete This Activity: 1 hour.

KW - Cardiac imaging

KW - Contrast echocardiography

KW - Contrast microbubbles

KW - Coronary artery disease

KW - Echocardiography

KW - Endocardial border definition

KW - Left ventricular ejection fraction

KW - Left ventricular opacification

KW - Myocardial contrast echocardiography

KW - Myocardial perfusion imaging

KW - Power Doppler imaging

KW - Real-time contrast echocardiography

KW - Stress echocardiography

KW - Ultrasound contrast agents

KW - Wall motion analysis

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