"Aligned-to-random" nanofiber scaffolds for mimicking the structure of the tendon-to-bone insertion site

Jingwei Xie, Xiaoran Li, Justin Lipner, Cionne N. Manning, Annie G. Schwartz, Stavros Thomopoulos, Younan Xia

Research output: Contribution to journalArticle

130 Citations (Scopus)

Abstract

We have demonstrated the fabrication of "aligned-to-random" electrospun nanofiber scaffolds that mimic the structural organization of collagen fibers at the tendon-to-bone insertion site. Tendon fibroblasts cultured on such a scaffold exhibited highly organized and haphazardly oriented morphologies, respectively, on the aligned and random portions.

Original languageEnglish (US)
Pages (from-to)923-926
Number of pages4
JournalNanoscale
Volume2
Issue number6
DOIs
StatePublished - Jun 14 2010

Fingerprint

Tendons
Nanofibers
Scaffolds
Bone
Fibroblasts
Scaffolds (biology)
Collagen
Fabrication
Fibers

ASJC Scopus subject areas

  • Materials Science(all)

Cite this

Xie, J., Li, X., Lipner, J., Manning, C. N., Schwartz, A. G., Thomopoulos, S., & Xia, Y. (2010). "Aligned-to-random" nanofiber scaffolds for mimicking the structure of the tendon-to-bone insertion site. Nanoscale, 2(6), 923-926. https://doi.org/10.1039/c0nr00192a

"Aligned-to-random" nanofiber scaffolds for mimicking the structure of the tendon-to-bone insertion site. / Xie, Jingwei; Li, Xiaoran; Lipner, Justin; Manning, Cionne N.; Schwartz, Annie G.; Thomopoulos, Stavros; Xia, Younan.

In: Nanoscale, Vol. 2, No. 6, 14.06.2010, p. 923-926.

Research output: Contribution to journalArticle

Xie, J, Li, X, Lipner, J, Manning, CN, Schwartz, AG, Thomopoulos, S & Xia, Y 2010, '"Aligned-to-random" nanofiber scaffolds for mimicking the structure of the tendon-to-bone insertion site', Nanoscale, vol. 2, no. 6, pp. 923-926. https://doi.org/10.1039/c0nr00192a
Xie, Jingwei ; Li, Xiaoran ; Lipner, Justin ; Manning, Cionne N. ; Schwartz, Annie G. ; Thomopoulos, Stavros ; Xia, Younan. / "Aligned-to-random" nanofiber scaffolds for mimicking the structure of the tendon-to-bone insertion site. In: Nanoscale. 2010 ; Vol. 2, No. 6. pp. 923-926.
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