Aldose Reductase Inhibitors: A Potential New Class of Agents for the Pharmacological Control of Certain Diabetic Complications

Peter F. Kador, Jin H. Kinoshita, Norman E. Sharpless

Research output: Contribution to journalArticle

274 Citations (Scopus)
Original languageEnglish (US)
Pages (from-to)841-849
Number of pages9
JournalJournal of Medicinal Chemistry
Volume28
Issue number7
DOIs
StatePublished - Jul 1985

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Sugar Alcohol Dehydrogenases
Phthalazines
Fluorenes
Rhodanine
Naphthalenes
Imidazoles
Hydantoins
Corneal Diseases
Animal Disease Models
Diabetic Angiopathies
Aldehyde Reductase
Molecular Models
Sorbitol
Diabetic Neuropathies
Diabetic Nephropathies
Diabetic Retinopathy
Tissue Distribution
Diabetes Complications
Structure-Activity Relationship
Substrate Specificity

ASJC Scopus subject areas

  • Molecular Medicine
  • Drug Discovery

Cite this

Aldose Reductase Inhibitors : A Potential New Class of Agents for the Pharmacological Control of Certain Diabetic Complications. / Kador, Peter F.; Kinoshita, Jin H.; Sharpless, Norman E.

In: Journal of Medicinal Chemistry, Vol. 28, No. 7, 07.1985, p. 841-849.

Research output: Contribution to journalArticle

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