Airway remodeling in asthma

Do histological changes and functional changes correlate?

Phil Lieberman, William J. Calhoun, Reynold A. Panettieri, Stephen P. Peters, Stephen Israel Rennard

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Asthma has traditionally been conceptualized as a reversible obstructive airway disease as opposed to an irreversible obstructive lung disease like emphysema or chronic bronchitis. However, evidence has been accumulating that-at least in some patients-the chronic inflammation of the airways associated with asthma leads to airway remodeling and possibly irreversible lung disease. According to Phil Lieberman, MD, who is Clinical Professor of Medicine and Pediatrics in the Divisions of Allergy and Immunology at the University of Tennessee College of Medicine in Cordova, primary-care physicians need to be concerned about remodeling in asthma because it indicates that an asthmatic patient may be at risk for developing a chronic, irreversible obstructive lung disease that will not respond to standardized therapy. Not all experts, however, are convinced. To more closely examine the issue of asthma and remodeling and its implications for primary-care physicians, Dr. Lieberman recently moderated the following Medical Crossfire with a panel of national experts.

Original languageEnglish (US)
Pages (from-to)34-47
Number of pages14
JournalMedical Crossfire
Volume4
Issue number5
StatePublished - Jan 1 2002

Fingerprint

Airway Remodeling
Asthma
Primary Care Physicians
Obstructive Lung Diseases
Clinical Medicine
Chronic Bronchitis
Emphysema
Allergy and Immunology
Chronic Obstructive Pulmonary Disease
Lung Diseases
Medicine
Pediatrics
Inflammation

ASJC Scopus subject areas

  • Medicine(all)
  • Health Policy

Cite this

Lieberman, P., Calhoun, W. J., Panettieri, R. A., Peters, S. P., & Rennard, S. I. (2002). Airway remodeling in asthma: Do histological changes and functional changes correlate? Medical Crossfire, 4(5), 34-47.

Airway remodeling in asthma : Do histological changes and functional changes correlate? / Lieberman, Phil; Calhoun, William J.; Panettieri, Reynold A.; Peters, Stephen P.; Rennard, Stephen Israel.

In: Medical Crossfire, Vol. 4, No. 5, 01.01.2002, p. 34-47.

Research output: Contribution to journalReview article

Lieberman, P, Calhoun, WJ, Panettieri, RA, Peters, SP & Rennard, SI 2002, 'Airway remodeling in asthma: Do histological changes and functional changes correlate?', Medical Crossfire, vol. 4, no. 5, pp. 34-47.
Lieberman P, Calhoun WJ, Panettieri RA, Peters SP, Rennard SI. Airway remodeling in asthma: Do histological changes and functional changes correlate? Medical Crossfire. 2002 Jan 1;4(5):34-47.
Lieberman, Phil ; Calhoun, William J. ; Panettieri, Reynold A. ; Peters, Stephen P. ; Rennard, Stephen Israel. / Airway remodeling in asthma : Do histological changes and functional changes correlate?. In: Medical Crossfire. 2002 ; Vol. 4, No. 5. pp. 34-47.
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