Avances en immunosupresión en trasplante hepático

Translated title of the contribution: Advances in immunossuppression in liver transplantation

Research output: Contribution to journalArticle

Abstract

The history of immunosuppression is a long one. From the utilization of steroids and azathioptine in the 50's to the design of humanized molecules that specifically block cell surface receptors. Liver transplantation is one of the procedures that benefit the most with the development of new immunosuppressors and is also one of the reasons to create a new branch in research and clinical practice: transplant medicine. It also set the standards for research in the "immunologic tolerance" field. The cornerstone in the post-liver transplant stage is the utilization of calcineurin inhibitors combined with new anti-metabolites and monoclonal antibodies. All these settings conforms a promising field in the research of new and better immunosuppressing agents.

Original languageSpanish
Pages (from-to)237-243
Number of pages7
JournalRevista de Investigacion Clinica
Volume57
Issue number2
StatePublished - Mar 1 2005

Fingerprint

Liver Transplantation
Research
Transplants
Cell Surface Receptors
Immunosuppression
Anti-Idiotypic Antibodies
History
Steroids
Monoclonal Antibodies
Medicine
Liver
Calcineurin Inhibitors

Keywords

  • Basiliximab
  • Cyclosporine
  • Daclizumab
  • Everolimus
  • FTY 720
  • Immunosuppressors
  • Mycophenolate mofetil
  • Tacrolimus

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Avances en immunosupresión en trasplante hepático. / Olivera-Martinez, Marco A.

In: Revista de Investigacion Clinica, Vol. 57, No. 2, 01.03.2005, p. 237-243.

Research output: Contribution to journalArticle

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