Administration of oral probiotic bacteria to pregnant women causes temporary infantile colonization

Michael Schultz, Claudia Göttl, Rose J. Young, Peter Charles Iwen, Jon A. Vanderhoof

Research output: Contribution to journalArticle

115 Citations (Scopus)

Abstract

It is difficult to permanently change the composition of the complex intestinal microflora of the adult. Orally administered probiotic bacteria produce only temporary colonization of the intestine in patients with a fully developed gut microflora. The gastrointestinal tract of a healthy fetus is sterile. During the birth process and rapidly thereafter, microbes from the mother and the surrounding environment colonize the gastrointestinal tract until a dense, complex microflora develops. Probiotic bacteria have been shown to beneficially influence the intestinal and systemic immune system and mediate protection against nosocomial infections affecting the neonate. The purpose of this study was to determine whether oral administration of the probiotic micro-organism Lactobacillus rhamnosus strain GG (L. GG) to the pregnant woman leads to colonization of the newborn infant.

Original languageEnglish (US)
Pages (from-to)293-297
Number of pages5
JournalJournal of pediatric gastroenterology and nutrition
Volume38
Issue number3
DOIs
StatePublished - Mar 2004

Fingerprint

Probiotics
Oral Administration
Pregnant Women
Bacteria
Gastrointestinal Tract
Newborn Infant
Lactobacillus rhamnosus
Cross Infection
Intestines
Immune System
Fetus
Mothers
Parturition
Gastrointestinal Microbiome

Keywords

  • Colonization
  • Infants
  • Pregnancy
  • Probiotic micro-organisms

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Gastroenterology

Cite this

Administration of oral probiotic bacteria to pregnant women causes temporary infantile colonization. / Schultz, Michael; Göttl, Claudia; Young, Rose J.; Iwen, Peter Charles; Vanderhoof, Jon A.

In: Journal of pediatric gastroenterology and nutrition, Vol. 38, No. 3, 03.2004, p. 293-297.

Research output: Contribution to journalArticle

Schultz, Michael ; Göttl, Claudia ; Young, Rose J. ; Iwen, Peter Charles ; Vanderhoof, Jon A. / Administration of oral probiotic bacteria to pregnant women causes temporary infantile colonization. In: Journal of pediatric gastroenterology and nutrition. 2004 ; Vol. 38, No. 3. pp. 293-297.
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