Addition of fat to the diets of Lactating sows: II. Effects on hormone-sensitive lipase activity, energy mobilization in response to epinephrine, and plasma insulin and glucose concentrations

S. L. Tilton, Phillip S Miller, A. J. Lewis, D. E. Reese, P. M. Ermer

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Four experiments were conducted to determine the effects of dietary fat on lipolysis in lactating sows. In Exp. 1, a 6 × 6 Latin square was used to determine the optimal dosage of epinephrine for use in a subsequent epinephrine challenge. Peak concentrations of plasma glucose and response area increased linearly (P < .10) with epinephrine dosage. However, plasma NEFA peak and response area were quadratically affected (P < .05 and .06, respectively) by epinephrine dosage, with a minimum NEFA peak concentration observed at .4 μg/kg and a maximum at 1.6 μg/kg. In Exp. 2, the effect of dietary tallow on the response to epinephrine infusion (1.6 μg/kg BW) was examined. No differences (P > .10) between treatments were observed in NEFA, glycerol, or peak concentrations of plasma glucose following epinephrine administration. In Exp. 3, the effect of dietary fat on hormone-sensitive lipase activity was examined. Sows (n = 36) were fed diets containing either 0 or 10% added tallow. Hormone-sensitive lipase activity on d 28 of lactation was increased by the addition of tallow to the diet (P = .06). No effect of dietary tallow was observed on hormone-sensitive lipase activity of adipose tissue on d 21 of lactation (P > .10) in Exp. 3 (n = 16 sows) and Exp. 4 (n = 30 sows). In summary, diets containing 10% added tallow did not alter the rate of lipolysis, as measured by exogenous epinephrine challenge, in adipose tissue of lactating sows.

Original languageEnglish (US)
Pages (from-to)2501-2509
Number of pages9
JournalJournal of animal science
Volume77
Issue number9
DOIs
StatePublished - Jan 1 1999

Fingerprint

Sterol Esterase
epinephrine
tallow
Epinephrine
sows
insulin
Fats
hormones
Insulin
Diet
Glucose
glucose
Lipolysis
Dietary Fats
energy
lipids
Lactation
diet
Adipose Tissue
lipolysis

Keywords

  • Fatty Acids
  • Glucose
  • Insulin
  • Lactation
  • Sows
  • Triacylglycerol Lipase

ASJC Scopus subject areas

  • Food Science
  • Animal Science and Zoology
  • Genetics

Cite this

Addition of fat to the diets of Lactating sows : II. Effects on hormone-sensitive lipase activity, energy mobilization in response to epinephrine, and plasma insulin and glucose concentrations. / Tilton, S. L.; Miller, Phillip S; Lewis, A. J.; Reese, D. E.; Ermer, P. M.

In: Journal of animal science, Vol. 77, No. 9, 01.01.1999, p. 2501-2509.

Research output: Contribution to journalArticle

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title = "Addition of fat to the diets of Lactating sows: II. Effects on hormone-sensitive lipase activity, energy mobilization in response to epinephrine, and plasma insulin and glucose concentrations",
abstract = "Four experiments were conducted to determine the effects of dietary fat on lipolysis in lactating sows. In Exp. 1, a 6 × 6 Latin square was used to determine the optimal dosage of epinephrine for use in a subsequent epinephrine challenge. Peak concentrations of plasma glucose and response area increased linearly (P < .10) with epinephrine dosage. However, plasma NEFA peak and response area were quadratically affected (P < .05 and .06, respectively) by epinephrine dosage, with a minimum NEFA peak concentration observed at .4 μg/kg and a maximum at 1.6 μg/kg. In Exp. 2, the effect of dietary tallow on the response to epinephrine infusion (1.6 μg/kg BW) was examined. No differences (P > .10) between treatments were observed in NEFA, glycerol, or peak concentrations of plasma glucose following epinephrine administration. In Exp. 3, the effect of dietary fat on hormone-sensitive lipase activity was examined. Sows (n = 36) were fed diets containing either 0 or 10{\%} added tallow. Hormone-sensitive lipase activity on d 28 of lactation was increased by the addition of tallow to the diet (P = .06). No effect of dietary tallow was observed on hormone-sensitive lipase activity of adipose tissue on d 21 of lactation (P > .10) in Exp. 3 (n = 16 sows) and Exp. 4 (n = 30 sows). In summary, diets containing 10{\%} added tallow did not alter the rate of lipolysis, as measured by exogenous epinephrine challenge, in adipose tissue of lactating sows.",
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