Addition of fat to the diets of Lactating sows: II. Effects on hormone-sensitive lipase activity, energy mobilization in response to epinephrine, and plasma insulin and glucose concentrations

S. L. Tilton, P. S. Miller, A. J. Lewis, D. E. Reese, P. M. Ermer

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Four experiments were conducted to determine the effects of dietary fat on lipolysis in lactating sows. In Exp. 1, a 6 × 6 Latin square was used to determine the optimal dosage of epinephrine for use in a subsequent epinephrine challenge. Peak concentrations of plasma glucose and response area increased linearly (P < .10) with epinephrine dosage. However, plasma NEFA peak and response area were quadratically affected (P < .05 and .06, respectively) by epinephrine dosage, with a minimum NEFA peak concentration observed at .4 μg/kg and a maximum at 1.6 μg/kg. In Exp. 2, the effect of dietary tallow on the response to epinephrine infusion (1.6 μg/kg BW) was examined. No differences (P > .10) between treatments were observed in NEFA, glycerol, or peak concentrations of plasma glucose following epinephrine administration. In Exp. 3, the effect of dietary fat on hormone-sensitive lipase activity was examined. Sows (n = 36) were fed diets containing either 0 or 10% added tallow. Hormone-sensitive lipase activity on d 28 of lactation was increased by the addition of tallow to the diet (P = .06). No effect of dietary tallow was observed on hormone-sensitive lipase activity of adipose tissue on d 21 of lactation (P > .10) in Exp. 3 (n = 16 sows) and Exp. 4 (n = 30 sows). In summary, diets containing 10% added tallow did not alter the rate of lipolysis, as measured by exogenous epinephrine challenge, in adipose tissue of lactating sows.

Original languageEnglish (US)
Pages (from-to)2501-2509
Number of pages9
JournalJournal of animal science
Volume77
Issue number9
DOIs
StatePublished - Sep 1999

Fingerprint

Sterol Esterase
epinephrine
tallow
Epinephrine
sows
insulin
Fats
hormones
Insulin
Diet
Glucose
glucose
Lipolysis
Dietary Fats
energy
lipids
Lactation
diet
Adipose Tissue
lipolysis

Keywords

  • Fatty Acids
  • Glucose
  • Insulin
  • Lactation
  • Sows
  • Triacylglycerol Lipase

ASJC Scopus subject areas

  • Food Science
  • Animal Science and Zoology
  • Genetics

Cite this

@article{228a8660c20149f58f29474a4cdbf6d5,
title = "Addition of fat to the diets of Lactating sows: II. Effects on hormone-sensitive lipase activity, energy mobilization in response to epinephrine, and plasma insulin and glucose concentrations",
abstract = "Four experiments were conducted to determine the effects of dietary fat on lipolysis in lactating sows. In Exp. 1, a 6 × 6 Latin square was used to determine the optimal dosage of epinephrine for use in a subsequent epinephrine challenge. Peak concentrations of plasma glucose and response area increased linearly (P < .10) with epinephrine dosage. However, plasma NEFA peak and response area were quadratically affected (P < .05 and .06, respectively) by epinephrine dosage, with a minimum NEFA peak concentration observed at .4 μg/kg and a maximum at 1.6 μg/kg. In Exp. 2, the effect of dietary tallow on the response to epinephrine infusion (1.6 μg/kg BW) was examined. No differences (P > .10) between treatments were observed in NEFA, glycerol, or peak concentrations of plasma glucose following epinephrine administration. In Exp. 3, the effect of dietary fat on hormone-sensitive lipase activity was examined. Sows (n = 36) were fed diets containing either 0 or 10{\%} added tallow. Hormone-sensitive lipase activity on d 28 of lactation was increased by the addition of tallow to the diet (P = .06). No effect of dietary tallow was observed on hormone-sensitive lipase activity of adipose tissue on d 21 of lactation (P > .10) in Exp. 3 (n = 16 sows) and Exp. 4 (n = 30 sows). In summary, diets containing 10{\%} added tallow did not alter the rate of lipolysis, as measured by exogenous epinephrine challenge, in adipose tissue of lactating sows.",
keywords = "Fatty Acids, Glucose, Insulin, Lactation, Sows, Triacylglycerol Lipase",
author = "Tilton, {S. L.} and Miller, {P. S.} and Lewis, {A. J.} and Reese, {D. E.} and Ermer, {P. M.}",
year = "1999",
month = "9",
doi = "10.2527/1999.7792501x",
language = "English (US)",
volume = "77",
pages = "2501--2509",
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TY - JOUR

T1 - Addition of fat to the diets of Lactating sows

T2 - II. Effects on hormone-sensitive lipase activity, energy mobilization in response to epinephrine, and plasma insulin and glucose concentrations

AU - Tilton, S. L.

AU - Miller, P. S.

AU - Lewis, A. J.

AU - Reese, D. E.

AU - Ermer, P. M.

PY - 1999/9

Y1 - 1999/9

N2 - Four experiments were conducted to determine the effects of dietary fat on lipolysis in lactating sows. In Exp. 1, a 6 × 6 Latin square was used to determine the optimal dosage of epinephrine for use in a subsequent epinephrine challenge. Peak concentrations of plasma glucose and response area increased linearly (P < .10) with epinephrine dosage. However, plasma NEFA peak and response area were quadratically affected (P < .05 and .06, respectively) by epinephrine dosage, with a minimum NEFA peak concentration observed at .4 μg/kg and a maximum at 1.6 μg/kg. In Exp. 2, the effect of dietary tallow on the response to epinephrine infusion (1.6 μg/kg BW) was examined. No differences (P > .10) between treatments were observed in NEFA, glycerol, or peak concentrations of plasma glucose following epinephrine administration. In Exp. 3, the effect of dietary fat on hormone-sensitive lipase activity was examined. Sows (n = 36) were fed diets containing either 0 or 10% added tallow. Hormone-sensitive lipase activity on d 28 of lactation was increased by the addition of tallow to the diet (P = .06). No effect of dietary tallow was observed on hormone-sensitive lipase activity of adipose tissue on d 21 of lactation (P > .10) in Exp. 3 (n = 16 sows) and Exp. 4 (n = 30 sows). In summary, diets containing 10% added tallow did not alter the rate of lipolysis, as measured by exogenous epinephrine challenge, in adipose tissue of lactating sows.

AB - Four experiments were conducted to determine the effects of dietary fat on lipolysis in lactating sows. In Exp. 1, a 6 × 6 Latin square was used to determine the optimal dosage of epinephrine for use in a subsequent epinephrine challenge. Peak concentrations of plasma glucose and response area increased linearly (P < .10) with epinephrine dosage. However, plasma NEFA peak and response area were quadratically affected (P < .05 and .06, respectively) by epinephrine dosage, with a minimum NEFA peak concentration observed at .4 μg/kg and a maximum at 1.6 μg/kg. In Exp. 2, the effect of dietary tallow on the response to epinephrine infusion (1.6 μg/kg BW) was examined. No differences (P > .10) between treatments were observed in NEFA, glycerol, or peak concentrations of plasma glucose following epinephrine administration. In Exp. 3, the effect of dietary fat on hormone-sensitive lipase activity was examined. Sows (n = 36) were fed diets containing either 0 or 10% added tallow. Hormone-sensitive lipase activity on d 28 of lactation was increased by the addition of tallow to the diet (P = .06). No effect of dietary tallow was observed on hormone-sensitive lipase activity of adipose tissue on d 21 of lactation (P > .10) in Exp. 3 (n = 16 sows) and Exp. 4 (n = 30 sows). In summary, diets containing 10% added tallow did not alter the rate of lipolysis, as measured by exogenous epinephrine challenge, in adipose tissue of lactating sows.

KW - Fatty Acids

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KW - Insulin

KW - Lactation

KW - Sows

KW - Triacylglycerol Lipase

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