Adaptation of the cortical somatosensory evoked potential following pulsed pneumatic stimulation of the lower face in adults

Rebecca Custead, Hyuntaek Oh, Austin Oder Rosner, Steven M Barlow

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Cortical adaptation to sustained sensory input is a pervasive form of short-term plasticity in neurological systems. Its role in sensory perception in health and disease, or predicting long-term plastic changes resulting from sensory training offers insight into the mechanisms of somatosensory and sensorimotor processing. A 4-channel electroencephalography (EEG) recording montage was placed bilaterally (C3-P3, C4-P4, F7-P3, F8-P4) to characterize the short-term effects of pulsed pneumatic orofacial stimulation on the cortical somatosensory evoked potential (cSEP) in twenty neurotypical adults (mean age=21±2.88 years). A servo-controlled pneumatic amplifier was used to deliver a repetitive series of pneumatic pulse trains (six 50-ms pulses, 5-second intertrain interval) through a linked pair of custom acetal homopolymer probes (aka TAC-Cells) adhered to the nonglabrous skin of the lower face proximal to the right oral angle to synchronously activate mechanoreceptive afferents in the trigeminal nerve. Blocks of pulse trains were counterbalanced among participants and delivered at two rates, 2 and 4 Hz. TAC-Cell stimulation of the lower face consistently evoked a series of cSEPs at P7, N20, P28, N38, P75, N85, and P115. The spatial organization and adaptation of the evoked cSEP was dependent on stimulus pulse index (1-6 within the pulse train, p=.012), frequency of stimulus presentation (2 vs 4 Hz, p<.001), component (P7-P115, p<.001), and recording montage (channels 1-4, p<.001). Early component latencies (P7-N20) were highly stable in polarity (sign) and latency, and consistent with putative far-field generators (e.g., trigeminal brainstem, ventroposteromedial thalamus).

Original languageEnglish (US)
Pages (from-to)81-90
Number of pages10
JournalBrain Research
Volume1622
DOIs
StatePublished - Oct 5 2015

Fingerprint

Somatosensory Evoked Potentials
Acetals
Trigeminal Nerve
Thalamus
Brain Stem
Electroencephalography
Skin
Health

Keywords

  • Electroencephalography (EEG)
  • Neuroplasticity
  • Pneumotactile stimulation
  • Trigeminal

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Cite this

Adaptation of the cortical somatosensory evoked potential following pulsed pneumatic stimulation of the lower face in adults. / Custead, Rebecca; Oh, Hyuntaek; Rosner, Austin Oder; Barlow, Steven M.

In: Brain Research, Vol. 1622, 05.10.2015, p. 81-90.

Research output: Contribution to journalArticle

@article{ab85dd5ce45c4848be494679718256f4,
title = "Adaptation of the cortical somatosensory evoked potential following pulsed pneumatic stimulation of the lower face in adults",
abstract = "Cortical adaptation to sustained sensory input is a pervasive form of short-term plasticity in neurological systems. Its role in sensory perception in health and disease, or predicting long-term plastic changes resulting from sensory training offers insight into the mechanisms of somatosensory and sensorimotor processing. A 4-channel electroencephalography (EEG) recording montage was placed bilaterally (C3-P3, C4-P4, F7-P3, F8-P4) to characterize the short-term effects of pulsed pneumatic orofacial stimulation on the cortical somatosensory evoked potential (cSEP) in twenty neurotypical adults (mean age=21±2.88 years). A servo-controlled pneumatic amplifier was used to deliver a repetitive series of pneumatic pulse trains (six 50-ms pulses, 5-second intertrain interval) through a linked pair of custom acetal homopolymer probes (aka TAC-Cells) adhered to the nonglabrous skin of the lower face proximal to the right oral angle to synchronously activate mechanoreceptive afferents in the trigeminal nerve. Blocks of pulse trains were counterbalanced among participants and delivered at two rates, 2 and 4 Hz. TAC-Cell stimulation of the lower face consistently evoked a series of cSEPs at P7, N20, P28, N38, P75, N85, and P115. The spatial organization and adaptation of the evoked cSEP was dependent on stimulus pulse index (1-6 within the pulse train, p=.012), frequency of stimulus presentation (2 vs 4 Hz, p<.001), component (P7-P115, p<.001), and recording montage (channels 1-4, p<.001). Early component latencies (P7-N20) were highly stable in polarity (sign) and latency, and consistent with putative far-field generators (e.g., trigeminal brainstem, ventroposteromedial thalamus).",
keywords = "Electroencephalography (EEG), Neuroplasticity, Pneumotactile stimulation, Trigeminal",
author = "Rebecca Custead and Hyuntaek Oh and Rosner, {Austin Oder} and Barlow, {Steven M}",
year = "2015",
month = "10",
day = "5",
doi = "10.1016/j.brainres.2015.06.025",
language = "English (US)",
volume = "1622",
pages = "81--90",
journal = "Brain Research",
issn = "0006-8993",
publisher = "Elsevier",

}

TY - JOUR

T1 - Adaptation of the cortical somatosensory evoked potential following pulsed pneumatic stimulation of the lower face in adults

AU - Custead, Rebecca

AU - Oh, Hyuntaek

AU - Rosner, Austin Oder

AU - Barlow, Steven M

PY - 2015/10/5

Y1 - 2015/10/5

N2 - Cortical adaptation to sustained sensory input is a pervasive form of short-term plasticity in neurological systems. Its role in sensory perception in health and disease, or predicting long-term plastic changes resulting from sensory training offers insight into the mechanisms of somatosensory and sensorimotor processing. A 4-channel electroencephalography (EEG) recording montage was placed bilaterally (C3-P3, C4-P4, F7-P3, F8-P4) to characterize the short-term effects of pulsed pneumatic orofacial stimulation on the cortical somatosensory evoked potential (cSEP) in twenty neurotypical adults (mean age=21±2.88 years). A servo-controlled pneumatic amplifier was used to deliver a repetitive series of pneumatic pulse trains (six 50-ms pulses, 5-second intertrain interval) through a linked pair of custom acetal homopolymer probes (aka TAC-Cells) adhered to the nonglabrous skin of the lower face proximal to the right oral angle to synchronously activate mechanoreceptive afferents in the trigeminal nerve. Blocks of pulse trains were counterbalanced among participants and delivered at two rates, 2 and 4 Hz. TAC-Cell stimulation of the lower face consistently evoked a series of cSEPs at P7, N20, P28, N38, P75, N85, and P115. The spatial organization and adaptation of the evoked cSEP was dependent on stimulus pulse index (1-6 within the pulse train, p=.012), frequency of stimulus presentation (2 vs 4 Hz, p<.001), component (P7-P115, p<.001), and recording montage (channels 1-4, p<.001). Early component latencies (P7-N20) were highly stable in polarity (sign) and latency, and consistent with putative far-field generators (e.g., trigeminal brainstem, ventroposteromedial thalamus).

AB - Cortical adaptation to sustained sensory input is a pervasive form of short-term plasticity in neurological systems. Its role in sensory perception in health and disease, or predicting long-term plastic changes resulting from sensory training offers insight into the mechanisms of somatosensory and sensorimotor processing. A 4-channel electroencephalography (EEG) recording montage was placed bilaterally (C3-P3, C4-P4, F7-P3, F8-P4) to characterize the short-term effects of pulsed pneumatic orofacial stimulation on the cortical somatosensory evoked potential (cSEP) in twenty neurotypical adults (mean age=21±2.88 years). A servo-controlled pneumatic amplifier was used to deliver a repetitive series of pneumatic pulse trains (six 50-ms pulses, 5-second intertrain interval) through a linked pair of custom acetal homopolymer probes (aka TAC-Cells) adhered to the nonglabrous skin of the lower face proximal to the right oral angle to synchronously activate mechanoreceptive afferents in the trigeminal nerve. Blocks of pulse trains were counterbalanced among participants and delivered at two rates, 2 and 4 Hz. TAC-Cell stimulation of the lower face consistently evoked a series of cSEPs at P7, N20, P28, N38, P75, N85, and P115. The spatial organization and adaptation of the evoked cSEP was dependent on stimulus pulse index (1-6 within the pulse train, p=.012), frequency of stimulus presentation (2 vs 4 Hz, p<.001), component (P7-P115, p<.001), and recording montage (channels 1-4, p<.001). Early component latencies (P7-N20) were highly stable in polarity (sign) and latency, and consistent with putative far-field generators (e.g., trigeminal brainstem, ventroposteromedial thalamus).

KW - Electroencephalography (EEG)

KW - Neuroplasticity

KW - Pneumotactile stimulation

KW - Trigeminal

UR - http://www.scopus.com/inward/record.url?scp=84940923255&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84940923255&partnerID=8YFLogxK

U2 - 10.1016/j.brainres.2015.06.025

DO - 10.1016/j.brainres.2015.06.025

M3 - Article

C2 - 26119917

AN - SCOPUS:84940923255

VL - 1622

SP - 81

EP - 90

JO - Brain Research

JF - Brain Research

SN - 0006-8993

ER -