Acute myeloid leukemia: Clinical Practice Guidelines in Oncology

Margaret R. O'Donnell, Frederick R. Appelbaum, Maria R. Baer, John C. Byrd, Steven E. Coutre, Lloyd E. Damon, Harry P. Erba, Eli Estey, James Foran, Jeffrey Lancet, Lori J. Maness, Peter G. Maslak, Michael Millenson, Joseph O. Moore, Donna Przepiorka, Paul Shami, B. Douglas Smith, Richard M. Stone, Martin S. Tallman

Research output: Contribution to journalReview article

18 Scopus citations


Approximately 11,960 people will be diagnosed with acute myeloid leukemia (AML) in 2005, and 9,000 patients will die of the disease. As the population ages, the incidence of AML, along with myelodysplasia, appears to be rising. Equally disturbing is the increasing incidence of treatment-related myelodysplasia and leukemia in survivors of tumors of childhood and young adulthood such as Hodgkin's disease, sarcomas, breast and testicular cancers, and lymphomas. Recent large clinical trials have highlighted the need for new, innovative strategies because outcomes for AML patients, particularly older patients, have not substantially changed in the past 3 decades.

Original languageEnglish (US)
Pages (from-to)16-36
Number of pages21
JournalJNCCN Journal of the National Comprehensive Cancer Network
Issue number1
StatePublished - Jan 1 2006



  • Acute myeloid leukemia
  • Chemotherapeutic agents
  • Cytogenetics
  • Leukemia treatment
  • NCCN Clinical Practice Guidelines

ASJC Scopus subject areas

  • Oncology

Cite this

O'Donnell, M. R., Appelbaum, F. R., Baer, M. R., Byrd, J. C., Coutre, S. E., Damon, L. E., Erba, H. P., Estey, E., Foran, J., Lancet, J., Maness, L. J., Maslak, P. G., Millenson, M., Moore, J. O., Przepiorka, D., Shami, P., Smith, B. D., Stone, R. M., & Tallman, M. S. (2006). Acute myeloid leukemia: Clinical Practice Guidelines in Oncology. JNCCN Journal of the National Comprehensive Cancer Network, 4(1), 16-36.