Acute Coronary Syndrome Symptom Clusters: Illustration of Results Using Multiple Statistical Methods

Catherine J. Ryan, Karen M. Vuckovic, Lorna Finnegan, Chang G. Park, Lani M Zimmerman, Bunny Pozehl, Paula Sue Schulz, Susan Ann Barnason, Holli A. DeVon

Research output: Contribution to journalArticle

Abstract

Researchers have employed various methods to identify symptom clusters in cardiovascular conditions, without identifying rationale. Here, we test clustering techniques and outcomes using a data set from patients with acute coronary syndrome. A total of 474 patients who presented to emergency departments in five United States regions were enrolled. Symptoms were assessed within 15 min of presentation using the validated 13-item ACS Symptom Checklist. Three variable-centered approaches resulted in four-factor solutions. Two of three person-centered approaches resulted in three-cluster solutions. K-means cluster analysis revealed a six-cluster solution but was reduced to three clusters following cluster plot analysis. The number of symptoms and patient characteristics varied within clusters. Based on our findings, we recommend using (a) a variable-centered approach if the research is exploratory, (b) a confirmatory factor analysis if there is a hypothesis about symptom clusters, and (c) a person-centered approach if the aim is to cluster symptoms by individual groups.

Original languageEnglish (US)
JournalWestern Journal of Nursing Research
DOIs
StateAccepted/In press - Jan 1 2019

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Acute Coronary Syndrome
Cluster Analysis
Checklist
Statistical Factor Analysis
Hospital Emergency Service
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Keywords

  • acute coronary syndrome
  • cluster analysis
  • latent class analysis
  • symptom clusters
  • symptoms

ASJC Scopus subject areas

  • Nursing(all)

Cite this

Acute Coronary Syndrome Symptom Clusters : Illustration of Results Using Multiple Statistical Methods. / Ryan, Catherine J.; Vuckovic, Karen M.; Finnegan, Lorna; Park, Chang G.; Zimmerman, Lani M; Pozehl, Bunny; Schulz, Paula Sue; Barnason, Susan Ann; DeVon, Holli A.

In: Western Journal of Nursing Research, 01.01.2019.

Research output: Contribution to journalArticle

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