Absolute blood velocity measured with a modified fundus camera

Donald D. Duncan, Paul Lemaillet, Mohamed Ibrahim, Quan Dong Nguyen, Matthias Hiller, Jessica Ramella-Roman

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

We present a new method for the quantitative estimation of blood flow velocity, based on the use of the Radon transform. The specific application is for measurement of blood flow velocity in the retina. Our modified fundus camera uses illumination from a green LED and captures imagery with a high-speed CCD camera. The basic theory is presented, and typical results are shown for an in vitro flow model using blood in a capillary tube. Subsequently, representative results are shown for representative fundus imagery. This approach provides absolute velocity and flow direction along the vessel center-line or any lateral displacement therefrom. We also provide an error analysis allowing estimation of confidence intervals for the estimated velocity.

Original languageEnglish (US)
Article number056014
JournalJournal of Biomedical Optics
Volume15
Issue number5
DOIs
StatePublished - Sep 1 2010

Fingerprint

blood flow
imagery
blood
Blood
flow velocity
Cameras
cameras
Flow velocity
capillary tubes
high speed cameras
retina
error analysis
radon
CCD cameras
vessels
confidence
Capillary tubes
Radon
light emitting diodes
illumination

Keywords

  • Absolute blood velocity
  • Flow
  • Perfusion
  • Radon transform

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Biomedical Engineering

Cite this

Duncan, D. D., Lemaillet, P., Ibrahim, M., Nguyen, Q. D., Hiller, M., & Ramella-Roman, J. (2010). Absolute blood velocity measured with a modified fundus camera. Journal of Biomedical Optics, 15(5), [056014]. https://doi.org/10.1117/1.3494565

Absolute blood velocity measured with a modified fundus camera. / Duncan, Donald D.; Lemaillet, Paul; Ibrahim, Mohamed; Nguyen, Quan Dong; Hiller, Matthias; Ramella-Roman, Jessica.

In: Journal of Biomedical Optics, Vol. 15, No. 5, 056014, 01.09.2010.

Research output: Contribution to journalArticle

Duncan, DD, Lemaillet, P, Ibrahim, M, Nguyen, QD, Hiller, M & Ramella-Roman, J 2010, 'Absolute blood velocity measured with a modified fundus camera', Journal of Biomedical Optics, vol. 15, no. 5, 056014. https://doi.org/10.1117/1.3494565
Duncan DD, Lemaillet P, Ibrahim M, Nguyen QD, Hiller M, Ramella-Roman J. Absolute blood velocity measured with a modified fundus camera. Journal of Biomedical Optics. 2010 Sep 1;15(5). 056014. https://doi.org/10.1117/1.3494565
Duncan, Donald D. ; Lemaillet, Paul ; Ibrahim, Mohamed ; Nguyen, Quan Dong ; Hiller, Matthias ; Ramella-Roman, Jessica. / Absolute blood velocity measured with a modified fundus camera. In: Journal of Biomedical Optics. 2010 ; Vol. 15, No. 5.
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