ABR measurements in the cat using a forward-masking paradigm

Michael P Gorga, J. McGee, E. J. Walsh, E. Javel, G. R. Farley

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Probe-elicited wave V amplitudes of the auditory brainstem response (ABR) were measured using a forward-masking paradigm. Subjects were anesthetized cats. For individual experiments, probe frequency and intensity were fixed and masker frequencies and intensities were varied. For each masker frequency, the extent to which the probe-elicited wave V amplitude was reduced by the preceding masker was plotted as a function of masker intensity. The rising segments of the masking functions were fitted with straight lines, using a least-squares procedure, to obtain estimates of their slopes. Masking grew most rapidly for masker frequencies below probe frequency, becoming progressively less steep as masker frequency increased. ABR tuning curves were constructed by using the linear fits to define the masker intensity that caused a 50% reduction in probe-elicited wave V amplitude. The shapes of these tuning curves were comparable to whole-nerve action potential (AP) tuning curves obtained under similar stimulus conditions. These results indicate that ABR amplitude measurements in a forward-masking paradigm can be used to estimate the growth of response to masking stimuli and frequency selectivity in a manner similar to AP amplitude measurments.

Original languageEnglish (US)
Pages (from-to)256-261
Number of pages6
JournalJournal of the Acoustical Society of America
Volume73
Issue number1
DOIs
StatePublished - Jan 1983

Fingerprint

cats
masking
probes
tuning
stimuli
curves
nerves
estimates
Paradigm
Masking
Hearing
selectivity
slopes
Tuning
Waves

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Acoustics and Ultrasonics

Cite this

ABR measurements in the cat using a forward-masking paradigm. / Gorga, Michael P; McGee, J.; Walsh, E. J.; Javel, E.; Farley, G. R.

In: Journal of the Acoustical Society of America, Vol. 73, No. 1, 01.1983, p. 256-261.

Research output: Contribution to journalArticle

Gorga, Michael P ; McGee, J. ; Walsh, E. J. ; Javel, E. ; Farley, G. R. / ABR measurements in the cat using a forward-masking paradigm. In: Journal of the Acoustical Society of America. 1983 ; Vol. 73, No. 1. pp. 256-261.
@article{ec8e56c2663e4030b924661b3b6214d3,
title = "ABR measurements in the cat using a forward-masking paradigm",
abstract = "Probe-elicited wave V amplitudes of the auditory brainstem response (ABR) were measured using a forward-masking paradigm. Subjects were anesthetized cats. For individual experiments, probe frequency and intensity were fixed and masker frequencies and intensities were varied. For each masker frequency, the extent to which the probe-elicited wave V amplitude was reduced by the preceding masker was plotted as a function of masker intensity. The rising segments of the masking functions were fitted with straight lines, using a least-squares procedure, to obtain estimates of their slopes. Masking grew most rapidly for masker frequencies below probe frequency, becoming progressively less steep as masker frequency increased. ABR tuning curves were constructed by using the linear fits to define the masker intensity that caused a 50{\%} reduction in probe-elicited wave V amplitude. The shapes of these tuning curves were comparable to whole-nerve action potential (AP) tuning curves obtained under similar stimulus conditions. These results indicate that ABR amplitude measurements in a forward-masking paradigm can be used to estimate the growth of response to masking stimuli and frequency selectivity in a manner similar to AP amplitude measurments.",
author = "Gorga, {Michael P} and J. McGee and Walsh, {E. J.} and E. Javel and Farley, {G. R.}",
year = "1983",
month = "1",
doi = "10.1121/1.388858",
language = "English (US)",
volume = "73",
pages = "256--261",
journal = "Journal of the Acoustical Society of America",
issn = "0001-4966",
publisher = "Acoustical Society of America",
number = "1",

}

TY - JOUR

T1 - ABR measurements in the cat using a forward-masking paradigm

AU - Gorga, Michael P

AU - McGee, J.

AU - Walsh, E. J.

AU - Javel, E.

AU - Farley, G. R.

PY - 1983/1

Y1 - 1983/1

N2 - Probe-elicited wave V amplitudes of the auditory brainstem response (ABR) were measured using a forward-masking paradigm. Subjects were anesthetized cats. For individual experiments, probe frequency and intensity were fixed and masker frequencies and intensities were varied. For each masker frequency, the extent to which the probe-elicited wave V amplitude was reduced by the preceding masker was plotted as a function of masker intensity. The rising segments of the masking functions were fitted with straight lines, using a least-squares procedure, to obtain estimates of their slopes. Masking grew most rapidly for masker frequencies below probe frequency, becoming progressively less steep as masker frequency increased. ABR tuning curves were constructed by using the linear fits to define the masker intensity that caused a 50% reduction in probe-elicited wave V amplitude. The shapes of these tuning curves were comparable to whole-nerve action potential (AP) tuning curves obtained under similar stimulus conditions. These results indicate that ABR amplitude measurements in a forward-masking paradigm can be used to estimate the growth of response to masking stimuli and frequency selectivity in a manner similar to AP amplitude measurments.

AB - Probe-elicited wave V amplitudes of the auditory brainstem response (ABR) were measured using a forward-masking paradigm. Subjects were anesthetized cats. For individual experiments, probe frequency and intensity were fixed and masker frequencies and intensities were varied. For each masker frequency, the extent to which the probe-elicited wave V amplitude was reduced by the preceding masker was plotted as a function of masker intensity. The rising segments of the masking functions were fitted with straight lines, using a least-squares procedure, to obtain estimates of their slopes. Masking grew most rapidly for masker frequencies below probe frequency, becoming progressively less steep as masker frequency increased. ABR tuning curves were constructed by using the linear fits to define the masker intensity that caused a 50% reduction in probe-elicited wave V amplitude. The shapes of these tuning curves were comparable to whole-nerve action potential (AP) tuning curves obtained under similar stimulus conditions. These results indicate that ABR amplitude measurements in a forward-masking paradigm can be used to estimate the growth of response to masking stimuli and frequency selectivity in a manner similar to AP amplitude measurments.

UR - http://www.scopus.com/inward/record.url?scp=0020549656&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020549656&partnerID=8YFLogxK

U2 - 10.1121/1.388858

DO - 10.1121/1.388858

M3 - Article

C2 - 6826893

AN - SCOPUS:0020549656

VL - 73

SP - 256

EP - 261

JO - Journal of the Acoustical Society of America

JF - Journal of the Acoustical Society of America

SN - 0001-4966

IS - 1

ER -