A Solid Phase Synthesis of Chalcones by Claisen-Schmidt Condensations

Mao Sheng Cheng, Rong Shi Li, George Kenyon

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

In order to accelerate the development of relatively inexpensive antimalarials that are effective against chloroquine-resistant strains of Plasmodium falclparum, a methodology for the solid phase synthesis of chalcone (1, 3-diphenyl-2-propen-l-one) analogues in reasonably high yields has been developed.

Original languageEnglish (US)
Pages (from-to)851-854
Number of pages4
JournalChinese Chemical Letters
Volume11
Issue number10
StatePublished - Oct 1 2000

Fingerprint

Chalcones
Chalcone
Chloroquine
Antimalarials
Condensation
diphenyl

Keywords

  • Antimalarial
  • Chalcones
  • Solid phase synthesis

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

A Solid Phase Synthesis of Chalcones by Claisen-Schmidt Condensations. / Cheng, Mao Sheng; Li, Rong Shi; Kenyon, George.

In: Chinese Chemical Letters, Vol. 11, No. 10, 01.10.2000, p. 851-854.

Research output: Contribution to journalArticle

Cheng, Mao Sheng ; Li, Rong Shi ; Kenyon, George. / A Solid Phase Synthesis of Chalcones by Claisen-Schmidt Condensations. In: Chinese Chemical Letters. 2000 ; Vol. 11, No. 10. pp. 851-854.
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