A reagent for the efficient cleavage of N-benzoylhomoserine lactones: Access to α-(2-phenylseleno)ethyl amino acids

Michelle L. Pedersen, David B. Berkowitz

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Upon heating diphenyl diselenide and sodium trimethoxyborohydride (1:2) in DMF to 60°C, a reagent is produced which efficiently cleaves α-substituted N-benzoylhomoserine lactones to the corresponding α-(2-phenylseleno)ethyl amino acids without competing lactone reduction.

Original languageEnglish (US)
Pages (from-to)7315-7318
Number of pages4
JournalTetrahedron Letters
Volume33
Issue number48
DOIs
StatePublished - Nov 24 1992

    Fingerprint

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this