A protocol to extend the longitudinal coverage of on-board cone-beam CT

Dandan Zheng, Jun Lu, Ariel Jefferson, Cheng Zhang, Jian Wu, William Sleeman, Elisabeth Weiss, Nesrin Dogan, Shiyu Song, Jeffrey Williamson

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The longitudinal coverage of a LINAC-mounted CBCT scan is limited to the corresponding dimensional limits of its flat panel detector, which is often shorter than the length of the treatment field. These limits become apparent when fields are designed to encompass wide regions, as when providing nodal coverage. Therefore, we developed a novel protocol to acquire double orbit CBCT images using a commercial system, and combine the images to extend the longitudinal coverage for image-guided adaptive radiotherapy (IGART). The protocol acquires two CBCT scans with a couch shift similar to the "step-and-shoot" cine CT acquisition, allowing a small longitudinal overlap of the two reconstructed volumes. An in-house DICOM reading/writing software was developed to combine the two image sets into one. Three different approaches were explored to handle the possible misalignment between the two image subsets: simple stacking, averaging the overlapped volumes, and a 3D-3D image registration with the three translational degrees of freedom. Using thermoluminescent dosimeters and custom-designed holders for a CTDI phantom set, dose measurements were carried out to assess the resultant imaging dose of the technique and its geometric distribution. Deformable registration was tested on patient images generated with the double-orbit protocol, using both the planning FBCT and the artificially deformed CBCT as source images. The protocol was validated on phantoms and has been employed clinically for IRB-approved IGART studies for head and neck and prostate cancer patients.

Original languageEnglish (US)
Pages (from-to)141-151
Number of pages11
JournalJournal of applied clinical medical physics
Volume13
Issue number4
DOIs
StatePublished - 2012

Fingerprint

Image-Guided Radiotherapy
Cone-Beam Computed Tomography
Radiotherapy
Orbit
Cones
cones
Orbits
Digital Imaging and Communications in Medicine (DICOM)
X Ray Computed Tomography
Dosimeters
Research Ethics Committees
Image registration
Head and Neck Neoplasms
Reading
Prostatic Neoplasms
Software
Detectors
Imaging techniques
Planning
radiation therapy

Keywords

  • Cbct
  • Field of view
  • Igart
  • Image registration

ASJC Scopus subject areas

  • Radiation
  • Instrumentation
  • Radiology Nuclear Medicine and imaging

Cite this

A protocol to extend the longitudinal coverage of on-board cone-beam CT. / Zheng, Dandan; Lu, Jun; Jefferson, Ariel; Zhang, Cheng; Wu, Jian; Sleeman, William; Weiss, Elisabeth; Dogan, Nesrin; Song, Shiyu; Williamson, Jeffrey.

In: Journal of applied clinical medical physics, Vol. 13, No. 4, 2012, p. 141-151.

Research output: Contribution to journalArticle

Zheng, D, Lu, J, Jefferson, A, Zhang, C, Wu, J, Sleeman, W, Weiss, E, Dogan, N, Song, S & Williamson, J 2012, 'A protocol to extend the longitudinal coverage of on-board cone-beam CT', Journal of applied clinical medical physics, vol. 13, no. 4, pp. 141-151. https://doi.org/10.1120/jacmp.v13i4.3796
Zheng, Dandan ; Lu, Jun ; Jefferson, Ariel ; Zhang, Cheng ; Wu, Jian ; Sleeman, William ; Weiss, Elisabeth ; Dogan, Nesrin ; Song, Shiyu ; Williamson, Jeffrey. / A protocol to extend the longitudinal coverage of on-board cone-beam CT. In: Journal of applied clinical medical physics. 2012 ; Vol. 13, No. 4. pp. 141-151.
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