A peritrophin-like protein expressed in the embryonic tracheae of Drosophila melanogaster

Mary K. Barry, Aleata A. Triplett, Alan C. Christensen

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

We have cloned and sequenced a cDNA from Drosophila melanogaster that encodes a protein homologous to the peritrophins, a family of chitin-binding proteins from the peritrophic matrix of insects. Unexpectedly, the gene, Gasp, is expressed in the embryonic tracheae. We suggest that this family of proteins may be present in other tissues than the peritrophic matrix, particularly where nutrient or gas exchange are important, and/or where invasion by parasites or viruses is possible. We have also mapped two similar genes that had been sequenced by the Berkeley Drosophila Genome Project, and find that these three very similar genes are not clustered, but are located oh three different chromosomes.

Original languageEnglish (US)
Pages (from-to)319-327
Number of pages9
JournalInsect Biochemistry and Molecular Biology
Volume29
Issue number4
DOIs
StatePublished - Apr 1 1999

Fingerprint

Trachea
Drosophila melanogaster
peritrophic membrane
Genes
Proteins
Chitin
genes
proteins
chitin
Drosophila
gas exchange
Insects
binding proteins
Carrier Proteins
Parasites
Chromosomes
Complementary DNA
Gases
Viruses
Genome

Keywords

  • Chitin
  • Drosophila melanogaster
  • Peritrophic matrix
  • Peritrophic membrane
  • Peritrophin
  • Tracheae
  • cDNA

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Insect Science

Cite this

A peritrophin-like protein expressed in the embryonic tracheae of Drosophila melanogaster. / Barry, Mary K.; Triplett, Aleata A.; Christensen, Alan C.

In: Insect Biochemistry and Molecular Biology, Vol. 29, No. 4, 01.04.1999, p. 319-327.

Research output: Contribution to journalArticle

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