A neurocomputational investigation of reinforcement-based decision making as a candidate latent vulnerability mechanism in maltreated children

Mattia I. Gerin, Vanessa B. Puetz, Robert James Blair, Stuart F White, Arjun Sethi, Ferdinand Hoffmann, Amy L. Palmer, Essi Viding, Eamon J. McCrory

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Alterations in reinforcement-based decision making may be associated with increased psychiatric vulnerability in children who have experienced maltreatment. A probabilistic passive avoidance task and a model-based functional magnetic resonance imaging analytic approach were implemented to assess the neurocomputational components underlying decision making: (a) reinforcement expectancies (the representation of the outcomes associated with a stimulus) and (b) prediction error signaling (the ability to detect the differences between expected and actual outcomes). There were three main findings. First, the maltreated group (n = 18; mean age = 13), relative to nonmaltreated peers (n = 19; mean age = 13), showed decreased activity during expected value processing in a widespread network commonly associated with reinforcement expectancies representation, including the striatum (especially the caudate), the orbitofrontal cortex, and medial temporal structures including the hippocampus and insula. Second, consistent with previously reported hyperresponsiveness to negative cues in the context of childhood abuse, the maltreated group showed increased prediction error signaling in the middle cingulate gyrus, somatosensory cortex, superior temporal gyrus, and thalamus. Third, the maltreated group showed increased activity in frontodorsal regions and in the putamen during expected value representation. These findings suggest that early adverse environments disrupt the development of decision-making processes, which in turn may compromise psychosocial functioning in ways that increase latent vulnerability to psychiatric disorder.

Original languageEnglish (US)
Pages (from-to)1689-1705
Number of pages17
JournalDevelopment and Psychopathology
Volume29
Issue number5
DOIs
StatePublished - Dec 1 2017

Fingerprint

Decision Making
Psychiatry
Aptitude
Somatosensory Cortex
Putamen
Gyrus Cinguli
Temporal Lobe
Prefrontal Cortex
Thalamus
Cues
Hippocampus
Magnetic Resonance Imaging
Reinforcement (Psychology)

ASJC Scopus subject areas

  • Developmental and Educational Psychology
  • Psychiatry and Mental health

Cite this

A neurocomputational investigation of reinforcement-based decision making as a candidate latent vulnerability mechanism in maltreated children. / Gerin, Mattia I.; Puetz, Vanessa B.; Blair, Robert James; White, Stuart F; Sethi, Arjun; Hoffmann, Ferdinand; Palmer, Amy L.; Viding, Essi; McCrory, Eamon J.

In: Development and Psychopathology, Vol. 29, No. 5, 01.12.2017, p. 1689-1705.

Research output: Contribution to journalArticle

Gerin, Mattia I. ; Puetz, Vanessa B. ; Blair, Robert James ; White, Stuart F ; Sethi, Arjun ; Hoffmann, Ferdinand ; Palmer, Amy L. ; Viding, Essi ; McCrory, Eamon J. / A neurocomputational investigation of reinforcement-based decision making as a candidate latent vulnerability mechanism in maltreated children. In: Development and Psychopathology. 2017 ; Vol. 29, No. 5. pp. 1689-1705.
@article{d9f2cf678b3a437788a5f54cf0d31bd9,
title = "A neurocomputational investigation of reinforcement-based decision making as a candidate latent vulnerability mechanism in maltreated children",
abstract = "Alterations in reinforcement-based decision making may be associated with increased psychiatric vulnerability in children who have experienced maltreatment. A probabilistic passive avoidance task and a model-based functional magnetic resonance imaging analytic approach were implemented to assess the neurocomputational components underlying decision making: (a) reinforcement expectancies (the representation of the outcomes associated with a stimulus) and (b) prediction error signaling (the ability to detect the differences between expected and actual outcomes). There were three main findings. First, the maltreated group (n = 18; mean age = 13), relative to nonmaltreated peers (n = 19; mean age = 13), showed decreased activity during expected value processing in a widespread network commonly associated with reinforcement expectancies representation, including the striatum (especially the caudate), the orbitofrontal cortex, and medial temporal structures including the hippocampus and insula. Second, consistent with previously reported hyperresponsiveness to negative cues in the context of childhood abuse, the maltreated group showed increased prediction error signaling in the middle cingulate gyrus, somatosensory cortex, superior temporal gyrus, and thalamus. Third, the maltreated group showed increased activity in frontodorsal regions and in the putamen during expected value representation. These findings suggest that early adverse environments disrupt the development of decision-making processes, which in turn may compromise psychosocial functioning in ways that increase latent vulnerability to psychiatric disorder.",
author = "Gerin, {Mattia I.} and Puetz, {Vanessa B.} and Blair, {Robert James} and White, {Stuart F} and Arjun Sethi and Ferdinand Hoffmann and Palmer, {Amy L.} and Essi Viding and McCrory, {Eamon J.}",
year = "2017",
month = "12",
day = "1",
doi = "10.1017/S095457941700133X",
language = "English (US)",
volume = "29",
pages = "1689--1705",
journal = "Development and Psychopathology",
issn = "0954-5794",
publisher = "Cambridge University Press",
number = "5",

}

TY - JOUR

T1 - A neurocomputational investigation of reinforcement-based decision making as a candidate latent vulnerability mechanism in maltreated children

AU - Gerin, Mattia I.

AU - Puetz, Vanessa B.

AU - Blair, Robert James

AU - White, Stuart F

AU - Sethi, Arjun

AU - Hoffmann, Ferdinand

AU - Palmer, Amy L.

AU - Viding, Essi

AU - McCrory, Eamon J.

PY - 2017/12/1

Y1 - 2017/12/1

N2 - Alterations in reinforcement-based decision making may be associated with increased psychiatric vulnerability in children who have experienced maltreatment. A probabilistic passive avoidance task and a model-based functional magnetic resonance imaging analytic approach were implemented to assess the neurocomputational components underlying decision making: (a) reinforcement expectancies (the representation of the outcomes associated with a stimulus) and (b) prediction error signaling (the ability to detect the differences between expected and actual outcomes). There were three main findings. First, the maltreated group (n = 18; mean age = 13), relative to nonmaltreated peers (n = 19; mean age = 13), showed decreased activity during expected value processing in a widespread network commonly associated with reinforcement expectancies representation, including the striatum (especially the caudate), the orbitofrontal cortex, and medial temporal structures including the hippocampus and insula. Second, consistent with previously reported hyperresponsiveness to negative cues in the context of childhood abuse, the maltreated group showed increased prediction error signaling in the middle cingulate gyrus, somatosensory cortex, superior temporal gyrus, and thalamus. Third, the maltreated group showed increased activity in frontodorsal regions and in the putamen during expected value representation. These findings suggest that early adverse environments disrupt the development of decision-making processes, which in turn may compromise psychosocial functioning in ways that increase latent vulnerability to psychiatric disorder.

AB - Alterations in reinforcement-based decision making may be associated with increased psychiatric vulnerability in children who have experienced maltreatment. A probabilistic passive avoidance task and a model-based functional magnetic resonance imaging analytic approach were implemented to assess the neurocomputational components underlying decision making: (a) reinforcement expectancies (the representation of the outcomes associated with a stimulus) and (b) prediction error signaling (the ability to detect the differences between expected and actual outcomes). There were three main findings. First, the maltreated group (n = 18; mean age = 13), relative to nonmaltreated peers (n = 19; mean age = 13), showed decreased activity during expected value processing in a widespread network commonly associated with reinforcement expectancies representation, including the striatum (especially the caudate), the orbitofrontal cortex, and medial temporal structures including the hippocampus and insula. Second, consistent with previously reported hyperresponsiveness to negative cues in the context of childhood abuse, the maltreated group showed increased prediction error signaling in the middle cingulate gyrus, somatosensory cortex, superior temporal gyrus, and thalamus. Third, the maltreated group showed increased activity in frontodorsal regions and in the putamen during expected value representation. These findings suggest that early adverse environments disrupt the development of decision-making processes, which in turn may compromise psychosocial functioning in ways that increase latent vulnerability to psychiatric disorder.

UR - http://www.scopus.com/inward/record.url?scp=85040550188&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85040550188&partnerID=8YFLogxK

U2 - 10.1017/S095457941700133X

DO - 10.1017/S095457941700133X

M3 - Article

VL - 29

SP - 1689

EP - 1705

JO - Development and Psychopathology

JF - Development and Psychopathology

SN - 0954-5794

IS - 5

ER -