Penicillinase (E.C.18.104.22.168) from Bacillus cereus 569/H is inhibited by Hg(II). The inhibition is characterized by non‐competitive kinetics and can be reversed by EDTA. A Hg(II) induced conformational change is indicated because: (1) The EDTA regenerated activity is unstable and is rapidly converted to an iodine‐sensitive state, and (2) An irreversible change in the circular dichroism spectrum at 222 nm is found.
|Original language||English (US)|
|Number of pages||9|
|Journal||International Journal of Peptide and Protein Research|
|State||Published - May 1975|
ASJC Scopus subject areas