A case of scopulariopsis brevicaulis endocarditis with mycotic aneurysm in an immunocompetent host

Kelly A Cawcutt, Larry M. Baddour, Mary Burgess

Research output: Contribution to journalArticle

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Abstract

Scopulariopsis is a genus of mold that is usually associated with onychomycosis and rarely causes complicated infection in immunocompetent persons. We describe a case of an immunocompetent 65-year-old male with a history of mitral valve repair with prosthetic ring placement who developed acute left posterior knee pain. Imaging showed a left popliteal artery aneurysm and thrombus, and further evaluation with transesophageal echocardiogram demonstrated two large, mobile mitral valve vegetations. He underwent debridement and replacement of the mitral valve, followed by debridement of the left popliteal artery with peroneal artery bypass. The intraoperative cultures grew Scopulariopsis brevicaulis. Due to the resistant nature of the organism, he was initially treated with combination antifungals including liposomal amphotericin B, caspofungin, and voriconazole and was continued on chronic suppression with posaconazole with no evidence of recurrence. Scopulariopsis is a rare cause of fungal endocarditis. Treatment of Scopulariopsis endocarditis is challenging and is not well understood due to its rarity.

Original languageEnglish (US)
Article number872871
JournalCase Reports in Medicine
Volume2015
DOIs
StatePublished - Jan 1 2015

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Scopulariopsis
Infected Aneurysm
Endocarditis
Mitral Valve
Popliteal Artery
Debridement
caspofungin
Onychomycosis
Aneurysm
Knee
Thrombosis
Fungi
Arteries
Recurrence
Pain
Infection

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A case of scopulariopsis brevicaulis endocarditis with mycotic aneurysm in an immunocompetent host. / Cawcutt, Kelly A; Baddour, Larry M.; Burgess, Mary.

In: Case Reports in Medicine, Vol. 2015, 872871, 01.01.2015.

Research output: Contribution to journalArticle

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