THE COCHLEAR TONOTOPIC MAP AT TWO STAGES OF DEVELOPMENT

Project: Research project

Description

The tonotopic map of the avian basilar papilla (Callus domesticus)
will be identified for two age groups (E16-17 and 2 weeks post
hatch). This will be undertaken to test the hypothesis that the
tonotopic map changes substantially throughout development and is
not simply a "scale model" of the adult. To accomplish this, individual eighth nerve neurons will be
impaled. The characteristic frequency and spontaneous rate will
be determined. Horseradish-peroxidase (HRP) will be
iontophoretically injected into the cell and allowed to distribute
throughout the cell as a cell tag. Terminals in the basilar
papilla will then be identified histologically and their position
expressed as a percent of the total length and width of the basilar
papilla.
StatusFinished
Effective start/end date5/1/884/30/90

Funding

  • National Institutes of Health

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cells
nerve tissue
peroxidase
callus
neurons
testing

ASJC

  • Medicine(all)
  • Neuroscience(all)