Development of technologies to support obesity and metabolic research

Project: Research project

Description

In this inaugural year of the Core, we commissioned the three large-size whole-room indirect calorimetry suites which were custom-built for 24-hr energy expenditure studies. To meet the needs of different study designs, the critical needs for these suites are measurement accuracy (between individuals), reproducibility (within individuals), comparability (between suites), and sensitivity (between time intervals). In the past year, we have successfully accomplished first two criteria, as such, two active protocols are using the suites regularly (07-DK-0077 and 07-DK-0202). We have laid the groundwork for further improvements of the suites in the areas of calibration, optimization of new algorithms, and stability, which will take place this coming year. Several new protocols will also be implemented in the metabolic suites. In addition, our efforts in the area of accelerometer development and validation are continuing. We now use these monitors to enhance our field meaurements of physical activity and energy expenditure.
StatusFinished
Effective start/end date4/1/058/31/16

Funding

  • National Institutes of Health: $265,791.00
  • National Institutes of Health: $265,791.00
  • National Institutes of Health: $90,000.00
  • National Institutes of Health: $322,988.00
  • National Institutes of Health: $311,684.00
  • National Institutes of Health: $322,988.00
  • National Institutes of Health: $263,133.00
  • National Institutes of Health: $322,988.00
  • National Institutes of Health: $271,215.00
  • National Institutes of Health: $260,502.00

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Nephrons
Knockout Mice
Large-Conductance Calcium-Activated Potassium Channels
Kidney
Rabbits
Gene Knockdown Techniques
Punctures
Diuretics
Electrolytes
Nitric Oxide
Phosphotransferases
Extremities
Adenosine Triphosphate
Crush Syndrome
Dogs
Calcium
Diet
Membranes
Hyperaldosteronism
Recycling

ASJC

  • Medicine(all)